Protein Alignment Esp and slc26a6

DIOPT Version :9

• Sequence 1: NP_001189282.1
• Gene: Esp / 42962
• FlyBaseID: FBgn0013953
• Length: 654
• Species: Drosophila melanogaster
• Sequence 2: NP_001072916.2
• Gene: slc26a6 / 780378
• XenbaseID: XB-GENE-919879
• Length: 735
• Species: Xenopus tropicalis
• Alignment Length: 677
• Identity: 163/677 - (24%)
• Similarity: 307/677 - (45%)
• Gaps: 147/677 - (21%)

  Fly    34 SNSVGSQGSKEFILTE--------DGKKVKPTVSTLDCTRSWLQDCQRRTFNRKTLHKRLPILGW 90
            :.:|....:::.:|:|        ..::|.|  |||...:..:: |. .:..:..|.|.:|||||
 Frog    12 NGAVMDPAARQLVLSEAELEEIAPRSQRVGP--STLARMKKRIR-CS-GSIAKSLLLKFIPILGW 72

  Fly    91 LPKYNSQD-AVGDLVAGITVGLTVIPQALAYAGIAGLPVAYGLYASFVGCFVYIFLGSCKDVPMG 154
            :|:|..:: .:||:|||::||:..:||.||||.:||:|..||||:||....:|...|:.:.:..|
 Frog    73 IPRYPVREWLLGDIVAGLSVGIIQLPQGLAYALLAGVPPVYGLYSSFFPVLLYAIFGTSRHISPG 137

  Fly   155 PSAIVALLTYQAAQGSWQKSVL-----------------------------LCLLSGIVELLMGL 190
            ..|:::::.     ||..:|::                             |..|.|:.::::||
 Frog   138 TFAVISVMV-----GSVTESLVPSELYTLPGNETLINITARDNDRVAVASALTFLVGLFQIMLGL 197

  Fly   191 FGLGFLIDFVSGPVSSGFTSAVSLIILTSQIQSVLG--ITAKGNTFVEIW--TQVFHNIEHTRAG 251
            ..:||::.::|.|:..|:|||.::.:..||::||||  |:.:.:....|:  ..:...:..|...
 Frog   198 VQVGFVVTYLSEPLIRGYTSAAAIHVTVSQMKSVLGVQISQRSHPLSLIYAIVNLCAKLPETNIA 262

  Fly   252 DTVLGLTCIVILLLMRSLSSCRIGPVDEKECSSFQRAVNKILWIVGTARNAILVVVCCIMGYMLH 316
            ..::|...|.:|.:::.|        ::|..|..:..:...|         |.::|...:.|..:
 Frog   263 SLLIGGIAITVLFVVKFL--------NDKYSSKIRMPIPIEL---------ITLIVATGISYGAN 310

  Fly   317 TEE-HGAPFRVVGEIPPGLPSIQLPPTSLTANETSNGVAEGFVEMVHSMGSGLVVIPLISLMENI 380
            ..: :|..  :|||||.|:.:..:|..|:.|:...|..|                |.::.....|
 Frog   311 LNQVYGVD--IVGEIPTGMKAPMVPNASIFASVVGNAFA----------------IAVVVYAFTI 357

  Fly   381 AICKAFA--NGKPVDASQELIAIGTANIFNSFVQAFPGTGALSRGAVNNASGVRTPLSNIYSGGL 443
            ::.|.||  :|..||::|||||:|.:|...||.|.|....|:||..|..::|..:.:::..|..:
 Frog   358 SLAKMFAVKHGYNVDSNQELIALGLSNSIGSFFQCFTIGTAMSRSLVQESTGGHSQVASAVSSLV 422

  Fly   444 VMIALLFLTPYFYFIPRPTLAAIIISAVVFMIEVKVVKPM-WRSKKSDLVPGVGTFVACLVLPLE 507
            ::|.:|.....|..:|:..|||:::..:..:.:.....|| |||.|.||:..|.||:|.::|.|:
 Frog   423 ILIIILRAGELFQTLPKAILAAVVVVNLKGIYKQFTDVPMLWRSNKIDLLVWVVTFLATILLNLD 487

  Fly   508 WGILIGVGLNVIFILYHAARPKLSTELLTTQSGVEYSMI-TPDRCLIFPSV---DYVRNLVNKQS 568
            .|:.:.|..:::.:::...:|             .||:: ..|...|:..|   |.|..:...:.
 Frog   488 IGLAVSVAFSLLTVIFRTQKP-------------HYSILGKVDNTDIYRDVAQFDQVTEIQGIKI 539

  Fly   569 IRQNVPVVIDASHVY--------GADFTTATVIDSLISDFNQRGQLLFFYNLKPSICSIFEHVSA 625
            .|.:..:....:::|        ||:      :|.||             .||..
 Frog   540 FRSSCTLYFANANLYAESVKRMCGAE------VDKLI-------------ELKKK---------- 575

  Fly   626 AQFVVYYQEQQLDELLKERNYVQKRLE 652
               .:..|:|..::..|:|....||.|
 Frog   576 ---AIKKQKQLQEKAEKQRKKENKRKE 599

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Esp	NP_001189282.1	sulP	86..615	CDD:273284	145/578 (25%)
		HCO3_cotransp	103..520	CDD:304903	119/453 (26%)
		STAS_SulP_like_sulfate_transporter	545..623	CDD:132913	14/89 (16%)
slc26a6	NP_001072916.2	sulP	68..711	CDD:273284	152/617 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000041
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1414
SonicParanoid	1	1.000	-	-		X49
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.940