Protein Alignment Esp and slc26a3.2

DIOPT Version :9

• Sequence 1: NP_001189282.1
• Gene: Esp / 42962
• FlyBaseID: FBgn0013953
• Length: 654
• Species: Drosophila melanogaster
• Sequence 2: NP_001035265.1
• Gene: slc26a3.2 / 563896
• ZFINID: ZDB-GENE-041210-179
• Length: 762
• Species: Danio rerio
• Alignment Length: 674
• Identity: 157/674 - (23%)
• Similarity: 281/674 - (41%)
• Gaps: 183/674 - (27%)

  Fly    42 SKEFILTEDGKKVKPTVSTLD-----CTRSWLQDCQRRTFNRKTLHKRLPILGWLPKYNSQD-AV 100
            |:|.:..|..|..:.....||     ||      |.........| ..||::||:..|:.:: .:
Zfish    17 SEEHLEEEHAKAYRKHKGLLDHIKLYCT------CTSERAKNAAL-SLLPVIGWMKIYSIKEWLL 74

  Fly   101 GDLVAGITVGLTVIPQALAYAGIAGLPVAYGLYASFVGCFVYIFLGSCKDVPMGPSAIVALL--- 162
            .|:|:|::.||..:.|.||::.:|.:...|||||:|....:|.|||:.:.:.:|...:::|:
Zfish    75 NDIVSGVSTGLVAVLQGLAFSLLASISTWYGLYAAFFPVIIYFFLGTSRHISVGAFPVLSLMVGA 139

  Fly   163 -------------TYQAAQGSWQK------SVLLCLLSGIVELLMGLFGLGFLIDFVSGPVSSGF 208
                         ...|.:|..::      |..|..|.|:.:|.|||..:||::.::|.|..|||
Zfish   140 VVTKLVPDEGPPANITAFEGLTKEEQRILVSASLTFLVGLFQLGMGLLQVGFIVMYLSEPYISGF 204

  Fly   209 TSAVSLIILTSQIQSVLGITAKG--NTFVEIWT--QVFHNIEHTRAGDTVLGLTCIVILLLMRSL 269
            |:|.::.||.||::.:||:|..|  .....|:|  .||..|..|...|.|..:..:|.:|.::.:
Zfish   205 TTAAAVHILVSQLKFILGLTVPGFSGPLSIIYTLESVFTQITSTNIHDLVTSIVVMVAVLAVKEI 269

  Fly   270 SSCRIGPVDEKECSSFQRAVNKILWIVGTARNAILVVVCCIMGYMLH-TEEHGAPFRVVGEIP-- 331
            :               .|..:|:  .|......|:.::.|.:.|..: .:.||..  |||:||
Zfish   270 N---------------DRFKSKL--PVPIPIEVIMTIIACGVSYAFNFRDNHGVD--VVGKIPNT 315

  Fly   332 ---PGLPSIQLPPTSLTANETSNGVAEGFVEMVHSMGS-GLVVIPLISLMENIAICKAFA--NGK 390
               |..|.:|                      |..|.: ....|.::......|:.|.::  :..
Zfish   316 FESPIAPDLQ----------------------VFQMAAVDAFPIAIVGFAVAFAVAKVYSVKHDY 358

  Fly   391 PVDASQELIAIGTANIFNSFVQAFPGTGALSRGAVNNASGVRTPLSNIYSGGLVMIALL----FL 451
            .:|.:|||||.|.:|||....:|...:.||||.||..::|.:|.::.:.|..:|::.:|    .|
Zfish   359 IIDGNQELIAFGASNIFGGSFKALAASTALSRSAVQESTGGKTQIAGLLSAIIVLVVILGIGFLL 423

  Fly   452 TPYFYFIPRPTLAAIIISAVVFMI-EVKVVKPMWRSKKSDLVPGVGTFVACLVLPLEWGILIGVG 515
            .|    :|:..|.|::|..:..|: :|..|..:|:..:.|.:..|||.:|.::|.|:.|:.:|:|
Zfish   424 EP----LPKSVLGAVVIVNLKGMLMQVVTVPYLWKKDRPDCIVWVGTCLAAIILGLDIGLAVGLG 484

  Fly   516 LNVIFILYHAARPKLSTELLTTQSGVEYSMITPDRCLI---FPSVDYVRNLVNKQSIRQNVPVVI 577
            |..:.:::.|..|                     ||.:   .|..|..|
Zfish   485 LEFLTVVFRAQFP---------------------RCCVLANIPGTDIYR---------------- 512

  Fly   578 DASHVYGADFTTATVIDSLISDFNQRG-------QLLFFYNLKPSICSIFEHVSAAQFVVYYQEQ 635
            |..|              .|:.|...|       ..:||.|::                 :::::
Zfish   513 DRKH--------------YINIFEPEGVKIFRIPSPIFFANIE-----------------FFRDK 546

  Fly   636 QLD-------ELLKERNYVQKRLE 652
            ..|       .:|::||...|:::
Zfish   547 LKDAVGFNPLRILRKRNKAVKKIK 570

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Esp	NP_001189282.1	sulP	86..615	CDD:273284	141/579 (24%)
		HCO3_cotransp	103..520	CDD:304903	121/456 (27%)
		STAS_SulP_like_sulfate_transporter	545..623	CDD:132913	13/87 (15%)
slc26a3.2	NP_001035265.1	sulP	59..705	CDD:273284	146/625 (23%)
		STAS_SulP_like_sulfate_transporter	517..701	CDD:132913	11/71 (15%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0659
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000041
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X49
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.810