Protein Alignment Esp and slc26a6l2

DIOPT Version :10

• Sequence 1: NP_524490.2
• Gene: Esp / 42962
• FlyBaseID: FBgn0013953
• Length: 654
• Species: Drosophila melanogaster
• Sequence 2: XP_685992.2
• Gene: slc26a6l2 / 557779
• ZFINID: ZDB-GENE-110408-11
• Length: 757
• Species: Danio rerio
• Alignment Length: 557
• Identity: 133/557 - (23%)
• Similarity: 261/557 - (46%)
• Gaps: 113/557 - (20%)

  Fly    85 LPILGWLPKYN-SQDAVGDLVAGITVGLTVIPQALAYAGIAGLPVAYGLYASFVGCFVYIFLGSC 148
            :|:|.|:|.|: .::.:||||:|::||:..:||.:|||.:|.:|..:|||.||....||...|:.
Zfish    67 MPVLSWIPCYSIRENGLGDLVSGVSVGIMHLPQGMAYALLASVPPVFGLYTSFYPVLVYFIFGTS 131

  Fly   149 KDVPMGPSAIVALLTYQ-----AAQGSW---------------------QKSVLLCLLSGIVELL 187
            |.:.:|..|:::::...     |..|.:                     :.:....||.||.::|
Zfish   132 KHISIGTFAVISIMIGSVSERLAPDGHFLTNGTNGLVVVDTEARDLQRLKVAAATTLLCGIFQVL 196

  Fly   188 MGLFGLGFLIDFVSGPVSSGFTSAVSLIILTSQIQSVLGITAKG--------NTFVEIWTQVFHN 244
            :|:...||::.::|.|:..|:|:..:...:|:|::.:.|::.:.        .|.||:...
Zfish   197 LGVVRFGFVVTYLSEPLVRGYTTGAAAHAITAQLKYMFGVSPRRFTGPLQLLYTLVELCGL---- 257

  Fly   245 IEHTRAGDTVLGLTCIVILLLMRSLSSC---RIG---PVDEKECSSFQRAVNKILWIVGTARNAI 303
            :..|.....|:.|..:..|::::.::||   |:.   |::                        :
Zfish   258 LPQTHVPTLVVSLVSLTALVIVKEINSCYSHRLPLPIPIE------------------------L 298

  Fly   304 LVVVC--CIMGYMLHTEEHGAPFRVVGEIPPGLPSIQLPPTSLTANETSNGVAEGFVEMVHSMGS 366
            :|:..  .|..|......:|..  ||||||.||    :||.          |.|  |....|:..
Zfish   299 MVITAGTLISHYTEMKTINGVD--VVGEIPKGL----MPPR----------VPE--VCFFSSVAG 345

  Fly   367 GLVVIPLISLMENIAICKAFA--NGKPVDASQELIAIGTANIFNSFVQAFPGTGALSRGAVNNAS 429
            ....:.::....:|::.|.||  :|..||::|||:|:|.:|....|.|.:..|.::||..:..::
Zfish   346 DAFAVAVVGYAISISLGKIFALKHGYKVDSNQELVALGLSNTIGGFFQCYAVTSSMSRSLIQEST 410

  Fly   430 GVRTPLSNIYSGGLVMIALLFLTPYFYFIPRPTLAAII-ISAVVFMIEVKVVKPMWRSKKSDLVP 493
            |.:|.::.:.|..:|:|.:|.|.|.|..:|...|:.|: ::.....::.:.:..:|||.|.||:.
Zfish   411 GGKTQVAGLISAVIVLITVLKLGPLFEELPTAVLSTIVFVNLKGMFMQCRDLPALWRSNKVDLLV 475

  Fly   494 GVGTFVACLVLPLEWGILIGVGLNVIFILYHAARPKLS-------TEL-LTTQS--------GVE 542
            .:.||:..::|.|:.|:...:...::.:::...||:.|       ||| |.|:|        |:
Zfish   476 WLVTFLCTVLLNLDLGLAASITFTLLTVIFRTQRPRYSLLGRVPDTELYLETESYKAAKAIPGI- 539

  Fly   543 YSMITPDRCLIFPSVD-YVRNLVNKQSIRQNVPVVID 578
             ::......:.:.:.: |...|:.|..|  |:|.:::
Zfish   540 -TIFRSSTMIYYANAELYHEALLEKSGI--NIPKILE 573

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Esp	NP_524490.2	SUL1	93..622	CDD:440424	129/549 (23%)
slc26a6l2	XP_685992.2	PRK11660	68..732	CDD:481320	133/556 (24%)