Protein Alignment Esp and Slc26a10

DIOPT Version :9

• Sequence 1: NP_001189282.1
• Gene: Esp / 42962
• FlyBaseID: FBgn0013953
• Length: 654
• Species: Drosophila melanogaster
• Sequence 2: NP_001128067.2
• Gene: Slc26a10 / 366909
• RGDID: 1564851
• Length: 684
• Species: Rattus norvegicus
• Alignment Length: 670
• Identity: 164/670 - (24%)
• Similarity: 277/670 - (41%)
• Gaps: 133/670 - (19%)

  Fly    51 GKKVKPTVSTLDCTRSWLQDCQRRTFNR-------KTLHKRLPILGWLPKYNSQD-AVGDLVAGI 107
            |.:.:|.:....|. .||...:||..:.       :.|..|||.|.|||:|..:. .:||.||||
  Rat    50 GAEQEPELPAEPCL-PWLCRLRRRRASACSGPGAWRVLLARLPPLRWLPQYRWRAWLLGDAVAGI 113

  Fly   108 TVGLTVIPQALAYAGIAGLPVAYGLYASFVGCFVYIFLGSCKDVPMGPSAIVALLTYQAAQGSWQ 172
            |||:..:||.:|:|.:..:|..:|||.||....:|..||:.:.:..|..|:::|:|     ||..
  Rat   114 TVGVVHVPQGMAFALLTSVPPVFGLYTSFFPVLIYSLLGTGRHLSTGTFAVLSLMT-----GSVV 173

  Fly   173 KSV----LLCLLSGIVE--------------------LLMGLF--GLGFLIDFVSGPVSSGFTSA 211
            :.|    |...||||..                    |::|:|  .||.|..|:|.||....||.
  Rat   174 ERVVPEPLAGNLSGIEREKLEAQRIGAAAAVAFGSGALMLGMFVLQLGVLSTFLSEPVVKALTSG 238

  Fly   212 VSLIILTSQIQSVLGITAKGNTFVEIWTQVFHNIEHTRAGDTVLGLTCIVIL----------LLM 266
            .:|.:|.||:.|:||::..                 .:.|...|..|...:|          |.:
  Rat   239 AALHVLVSQLPSLLGLSLP-----------------RQIGCFSLFKTLAAVLSALNQSSPAELTI 286

  Fly   267 RSLSSCRIGPVDEKECSSFQRAVNKILWIVGTARNAILVVVCCIMGYMLHTEEHGAPFRVVGEIP 331
            .:||...:.||.|.......|....   |.|.....:|..|.|....:    :.....:|||.:|
  Rat   287 SALSLALLVPVKELNVRFRDRLPTP---IPGEVVMVLLATVLCFTSSL----DSRYNVQVVGLLP 344

  Fly   332 PGLPSIQLPPTSLTANETSNGVAEGFVEMVHSMGSGLVVIPLISLMENIAICKAFAN--GKPVDA 394
            .|.|...||    |.::....:|:.            :.|.|::...:.::...:|:  ...:|.
  Rat   345 GGFPQPLLP----TLDDLPRILADS------------LPISLVTFAVSTSLASIYADKYSYTIDP 393

  Fly   395 SQELIAIGTANIFNSFVQAFPGTGALSRGAVNNASGVRTPLSNIYSGGLVMIALLFLTPYFYFIP 459
            :|||:|.|.:|:.:|....||.:..|:..::...:|..|.||.::|..:|:..||:|.|:||::|
  Rat   394 NQELLAHGVSNLISSLFSCFPNSATLATTSLLVDAGGNTQLSGLFSCTVVLSVLLWLGPFFYYLP 458

  Fly   460 RPTLAAIIISAVVFM-IEVKVVKPMWRSKKSDLVPGVGTFVACLVLPLEWGILIGVGLNVIFILY 523
            :..||.|.||::..| .:::.:..:|...:.|....:.|:||.:.|.::.|:.:||.::::.::.
  Rat   459 KAVLACINISSMRQMFFQMQELPQLWHVSRVDFAVWMVTWVAVVTLNVDLGLAVGVVVSMVTVVC 523

  Fly   524 HAARPKL-------STELLTTQSGVEYSMITPDRCLI-FPSVDYV------------------RN 562
            ...|.|.       .|||..........:..|..|:: :|:..|.                  |.
  Rat   524 RTQRVKCLALGLAEGTELYRPIRESHKLLQVPGLCILSYPAPLYFATRGQFHRVLEWHLGLGERT 588

  Fly   563 LVNKQSIRQNVPVVIDASHVYGADFTTATVIDSLISDFNQRGQLLFFYNLKPSICSIFEHVSAAQ 627
            ....:.||   .|::|.|.|..||...|..:..|.......|           ||.:....:...
  Rat   589 KPGAEPIR---VVILDFSGVTFADAAGAREVVQLTRRCQDDG-----------ICLLLAQCNDLV 639

  Fly   628 FVVYYQEQQLDELLKERNYV 647
            .....:...||.:..|:.:|
  Rat   640 LKTLTRAGLLDSMTPEQLFV 659

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Esp	NP_001189282.1	sulP	86..615	CDD:273284	148/594 (25%)
		HCO3_cotransp	103..520	CDD:304903	119/455 (26%)
		STAS_SulP_like_sulfate_transporter	545..623	CDD:132913	18/96 (19%)
Slc26a10	NP_001128067.2	sulP	91..664	CDD:273284	154/628 (25%)
		STAS_SulP_like_sulfate_transporter	553..661	CDD:132913	22/121 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0659
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000041
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X49
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.810