DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Esp and Slc26a9

DIOPT Version :9

Sequence 1:	NP_001189282.1	Gene:	Esp / 42962	FlyBaseID:	FBgn0013953	Length:	654	Species:	Drosophila melanogaster
Sequence 2:	NP_001100642.1	Gene:	Slc26a9 / 304784	RGDID:	1310441	Length:	790	Species:	Rattus norvegicus

Alignment Length:	516	Identity:	134/516 - (25%)
Similarity:	235/516 - (45%)	Gaps:	97/516 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    51 GKKVKPTVSTLDCTRSWLQDCQRRTFNRKTLHKRLPILGWLPKYNSQD-AVGDLVAGITVGLTVI 114
            |:|::   :|..|:.:.|         :..:...||:|.|||||..:| .:.||:.|::.|...:
  Rat    34 GEKLR---NTFRCSSAKL---------KAIVFGLLPVLSWLPKYKIKDYIIPDLLGGLSGGCIQV 86

  Fly   115 PQALAYAGIAGLPVAYGLYASFVGCFVYIFLGSCKDVPMGPSAIVALLT-----YQAAQGSWQ-- 172
            ||.:|:|.:|.||...|||:||.....|.|||....:..|..|::::|.     ..|.:..:|
  Rat    87 PQGMAFALLANLPAVNGLYSSFFPLLTYFFLGGIHQMVPGTFAVISILVGNICLQLAPESKFQIF 151

  Fly   173 --------------------KSVLLCLLSGIVELLMGLFGLGFLIDFVSGPVSSGFTSAVSLIIL 217
                                .|..|..|:.::::.:|....||:..::|.....||.:|..|.||
  Rat   152 NATTNETYVDTVAMEAERLHVSATLACLTAVIQMALGFMQFGFVAIYLSESFIRGFMTAAGLQIL 216

  Fly   218 TSQIQSVLGITAKGNT----FVEIWTQVFHNIEHTRAGDTVLGLTCIVILLLMRSLSSCRIGPVD 278
            .|.::.:.|:|....|    .|..:..:..|:.||.....|..|...|.|:|::.|::
  Rat   217 ISVLKYIFGLTIPSYTGPGSIVFTFIDICKNLPHTNIASLVFALVSGVFLVLVKELNA------- 274

  Fly   279 EKECSSFQRAVNKILWIVGTARNAILVVVC------CIMGYMLHTEEHGAPFRVVGEIPPGLPSI 337
                    |.::||.:.:.|  ..|:|||.      |.|....|       .::||||..|.| |
  Rat   275 --------RYMHKIHFPIPT--EMIVVVVATAISGSCKMPKKYH-------MQIVGEIRHGFP-I 321

  Fly   338 QLPPTSLTANETSNGVAEGFVEMVHSMGSGLVVIPLISLMENIAICKAFAN--GKPVDASQELIA 400
            .:.|           :...:.:||.:..|    :.::..:.|:|:.:..||  |..||::||:||
  Rat   322 PVAP-----------MVSQWKDMVGTAFS----LAIVGYVINLAMGRTLANKHGYDVDSNQEMIA 371

  Fly   401 IGTANIFNSFVQAFPGTGALSRGAVNNASGVRTPLSNIYSGGLVMIALLFLTPYFYFIPRPTLAA 465
            :|.:|.|.||.:......|||.....:.:|.::.::::....:|||.:|.|..|.|.:|:..|.|
  Rat   372 LGCSNFFGSFFKIHVICCALSVTLAVDGAGGKSQVASLCVSLVVMITMLVLGSYLYPLPKAVLGA 436

  Fly   466 IIISAVVFMIEVK-VVKP--MWRSKKSDLVPGVGTFVACLVLPLEWGILIGVGLNVIFILY 523
            :|  ||.....:| :..|  :||..|.|....|.:|::...|.|.:|:.:||..:::.:::
  Rat   437 LI--AVNLKNSLKQLTDPYYLWRKSKLDCCVWVVSFLSSFFLSLPYGVAVGVAFSILVVIF 495

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Esp	NP_001189282.1	sulP	86..615	CDD:273284	128/481 (27%)
		HCO3_cotransp	103..520	CDD:304903	119/458 (26%)
		STAS_SulP_like_sulfate_transporter	545..623	CDD:132913
Slc26a9	NP_001100642.1	sulP	57..733	CDD:273284	128/481 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0659
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X49
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.810