Protein Alignment Esp and Slc26a7

DIOPT Version :10

• Sequence 1: NP_524490.2
• Gene: Esp / 42962
• FlyBaseID: FBgn0013953
• Length: 654
• Species: Drosophila melanogaster
• Sequence 2: XP_038965346.1
• Gene: Slc26a7 / 297910
• RGDID: 1310846
• Length: 692
• Species: Rattus norvegicus
• Alignment Length: 621
• Identity: 145/621 - (23%)
• Similarity: 256/621 - (41%)
• Gaps: 137/621 - (22%)

  Fly    38 GSQGSKEFILTEDGKKVKPTVSTLDCTRSWLQDCQRRTFNRKTLHKRLPILGWLPKYN-SQDAVG 101
            |::..|..:|.  ||...|....:   :.|   |:|          |||||.|.|:|| .::.:.
  Rat     3 GAKRKKRSVLW--GKMHTPHREDI---KQW---CKR----------RLPILEWAPQYNLKENLLP 49

  Fly   102 DLVAGITVGLTVIPQALAYAGIAGLPVAYGLYASFVGCFVYIFLGSCKDVPMGPSAIVALLTYQA 166
            |.|:|:.:.:..:.|.|::|.::.:...:|||.|.....:|...|..:.|..|..|:.:|::..|
  Rat    50 DTVSGVLLAVQQVTQGLSFAILSSVHPVFGLYGSLFPAIIYAIFGMGRHVATGTFALTSLISANA 114

  Fly   167 AQ-----------GSWQKSVL---------------LCLLSGIVELLMGLFGLGFLIDFVSGPVS 205
            .:           .....|||               :..|.|:::|:|.:..||.....::.||.
  Rat   115 VERLVPQSNRNLTTQSNSSVLGLSEFELQRIGVAAAVSFLGGVIQLVMFVLQLGNATFLLTEPVI 179

  Fly   206 SGFTSAVSLIILTSQIQSVLGITAKGNT----FVEIWTQVFHNIEHTRAGDTVLGLTCIVILLLM 266
            |..|:..:..::|||::.:|||.....:    |..|:..||.||:..:....:|.|..||:|:|:
  Rat   180 SAMTTGAATHVVTSQVKYLLGIKMPYISGPLGFFYIYAYVFENIKSVQLEALLLSLLSIVVLVLV 244

  Fly   267 RSLSSCRIGPVDEKECSSFQRAVNKILWIVGTARNAILVVVCCIMGYMLHTEE-HGAPFRVVGEI 330
            :.|:            ..|:|.:..:|.:     :.:|::......|..:.|. :|  ..|||.|
  Rat   245 KELN------------EQFKRKIKVVLPV-----DLVLIIAASFACYCTNMENTYG--LEVVGRI 290

  Fly   331 PPGLPSIQLPPTSLTANETSNGVAEGFVEMVHSMGSGLVVIPLISLMENIAICKAFAN--GKPVD 393
            |.|:|    ||.:...|..|..:.|.|            .:.|:..:.::|:.:..|.  ...||
  Rat   291 PKGIP----PPRAPPMNILSAVLTEAF------------GVALVGYVASLALAQGSAKKFKYSVD 339

  Fly   394 ASQELIAIGTANIFNSFVQAFPGTGALSRGAVNNASGVRTPLSNIYSGGLVMIALLFLTPYFYFI 458
            .:||.:|.|.:|:..||:...|...|:.|.|...::|.:|.::.:.|...|:|.:..:.|..|::
  Rat   340 DNQEFLAHGLSNVIPSFLFCIPSAAAMGRTAGLYSTGAKTQVACLISCIFVLIVIYAIGPLLYWL 404

  Fly   459 PRPTLAAIIISAVV-FMIEVKVVKPMWRSKKSDLVPGVGTFVACLVLPLEWGILIGVGLNVIFIL 522
            |...||:||:..:. .:|:.:.:|..|...|.|....:.|::..:......|:|.||...:..:|
  Rat   405 PMCVLASIIVVGLKGMLIQFRDLKKYWNVDKIDWGIWISTYIFTICFAANVGLLFGVVCTIAIVL 469

  Fly   523 YHAAR----------------------------PKLSTEL------LTTQSGVEYSMITPDRCLI 553
            ....|                            |..||.:      |.|.|.|....:||
  Rat   470 GRFPRAKTLSITDMKEMELKVKTETYDNTENWPPSKSTNVKVFPGSLKTGSNVRSLSVTP----- 529

  Fly   554 FPSVDYVRNLVNKQSIR---QNVPVVIDASHVYGAD 586
                   |.:.|.|.|:   .|.|:|...:..:.||
  Rat   530 -------RRMENSQQIKIISINNPLVFLNAKKFSAD 558

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Esp	NP_524490.2	SUL1	93..622	CDD:440424	129/566 (23%)
Slc26a7	XP_038965346.1	PRK11660	33..673	CDD:481320	134/573 (23%)