Protein Alignment Esp and Slc26a1

DIOPT Version :10

• Sequence 1: NP_524490.2
• Gene: Esp / 42962
• FlyBaseID: FBgn0013953
• Length: 654
• Species: Drosophila melanogaster
• Sequence 2: NP_001297620.1
• Gene: Slc26a1 / 231583
• MGIID: 2385894
• Length: 720
• Species: Mus musculus
• Alignment Length: 543
• Identity: 135/543 - (24%)
• Similarity: 241/543 - (44%)
• Gaps: 104/543 - (19%)

  Fly    39 SQGSKEFILTEDGKKVKPTVSTLDCTRSWLQDCQRRTFNRKTLHKRLPILGWLPKYNSQD-AVGD 102
            |||..|   |...:..|....::.|.::.:|..             .|.:.|||:|..:: ..||
Mouse    40 SQGLLE---TLKARLKKSCTCSMPCAQALVQGL-------------FPAIHWLPQYRLKEYLAGD 88

  Fly   103 LVAGITVGLTVIPQALAYAGIAGLPVAYGLYASFVGCFVYIFLGSCKDVPMGPSAIVALLTYQAA 167
            :::|:.:|:.::|||:||:.:|||...|.||.||....:|..:|:.:.|.:|..:::.|:..|..
Mouse    89 VMSGLVIGIILVPQAIAYSLLAGLQPIYSLYTSFFANLIYFLMGTSRHVNVGIFSLLCLMVGQVV 153

  Fly   168 QGSWQ------------------------------------------KSVLLCLLSGIVELLMGL 190
            ....|                                          .:..|.|::|:.::|||:
Mouse   154 DRELQLAGFDPSQDSLGPKNNDSTLNNSATTLIIGLQDCRRDCYAIRVATALTLMAGLYQVLMGI 218

  Fly   191 FGLGFLIDFVSGPVSSGFTSAVSLIILTSQIQSVLGITAKGN----TFVEIWTQVFHNIEHTRAG 251
            ..|||:..::|.|:..||....|:.|||||.:.:||:....:    ..|..|..:..|:......
Mouse   219 LRLGFVSTYLSQPLLDGFAMGASVTILTSQAKHMLGVQIPRHQGLGMVVHTWLSLLQNVGQANIC 283

  Fly   252 DTVLGLTCIVILLLMRSLSSCRIGPVDEKECSSFQRAVNKILWIVGTARNAILVVVCCIMGY--M 314
            |.|....|:.:||..:.||               .|..:::...:.|  ...::||..|:.:  .
Mouse   284 DVVTSALCLGVLLAAKELS---------------DRYRHRLKVPIPT--ELFVIVVATIVSHFGQ 331

  Fly   315 LHTEEHGAPFRVVGEIPPGLPSIQLPPTSLTANETSNGVAEGFVEMVHSMGSGLVVIPLISLMEN 379
            |||....   ||.|.||.|..:.|:|...:......:.::                :.|:....:
Mouse   332 LHTRFDS---RVAGNIPTGFVAPQVPDPKIMWRVALDAMS----------------LALVGSAFS 377

  Fly   380 IAICKAFA--NGKPVDASQELIAIGTANIFNSFVQAFPGTGALSRGAVNNASGVRTPLSNIYSGG 442
            |::.:.||  :|..|.|:|||:|:|..|:..:|...|..:.|||:..|..|:|.:|.||::.|..
Mouse   378 ISLAEMFARSHGYSVSANQELLAVGCCNVLPAFFHCFATSAALSKTLVKIATGCQTQLSSVVSAA 442

  Fly   443 LVMIALLFLTPYFYFIPRPTLAAIIISAVVFMI-EVKVVKPMWRSKKSDLVPGVGTFVACLVLPL 506
            :|::.||.|.|.|:.:.|..||.||:.::...: :||.:..:||...:|.:..|.|...|:::..
Mouse   443 VVLLVLLVLAPLFHDLQRCVLACIIVVSLRGALRKVKDLPQLWRLSPADALVWVATAATCVLVST 507

  Fly   507 EWGILIGVGLNVIFILYHAARPK 529
            |.|:|.||..:::.:.....||:
Mouse   508 EAGLLAGVFFSLLSLAGRTQRPR 530

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Esp	NP_524490.2	SUL1	93..622	CDD:440424	123/489 (25%)
Slc26a1	NP_001297620.1	sulP	71..702	CDD:273284	127/496 (26%)