Protein Alignment Esp and Slc26a2

DIOPT Version :9

• Sequence 1: NP_001189282.1
• Gene: Esp / 42962
• FlyBaseID: FBgn0013953
• Length: 654
• Species: Drosophila melanogaster
• Sequence 2: NP_031911.1
• Gene: Slc26a2 / 13521
• MGIID: 892977
• Length: 739
• Species: Mus musculus
• Alignment Length: 575
• Identity: 138/575 - (24%)
• Similarity: 254/575 - (44%)
• Gaps: 109/575 - (18%)

  Fly    43 KEFILTEDGKKVKPTVSTLDCTRSWLQDCQRRTFNRKTLHKRLPILGWLPKYN-SQDAVGDLVAG 106
            |:|::.|..|       :..|:.:.::|.....|         |:|.|||||: .::.:||:::|
Mouse    67 KQFVIRELQK-------SCQCSAAKVRDGAFDFF---------PVLRWLPKYDLKKNILGDVMSG 115

  Fly   107 ITVGLTVIPQALAYAGIAGLPVAYGLYASFVGCFVYIFLGSCKDVPMGPSAIVALLTYQAAQGSW 171
            :.||:.::||::||:.:||....||||.||....:|...|:.:.:.:|...|:.|:..:......
Mouse   116 LIVGILLVPQSIAYSLLAGQEPIYGLYTSFFASIIYFLFGTSRHISVGIFGILCLMIGEVVDREL 180

  Fly   172 QKSVL-------------------------LC--------------LLSGIVELLMGLFGLGFLI 197
            .|:..                         ||              .::|:.::.||.|.:||:.
Mouse   181 HKACPDTDATSSSIAVFSSGCVVVNHTLDGLCDKSCYAIKIGSTVTFMAGVYQVAMGFFQVGFVS 245

  Fly   198 DFVSGPVSSGFTSAVSLIILTSQIQSVLGITAKGN----TFVEIWTQVFHNIEHTRAGDTVLGLT 258
            .::|..:.|||.:..|..|||||.:.:||::...:    :.:..|..:|.||.:|...|.:..|.
Mouse   246 VYLSDALLSGFVTGASFTILTSQAKYLLGLSLPRSHGVGSVITTWIHIFRNIRNTNICDLITSLL 310

  Fly   259 CIVILLLMRSLSSCRIGPVDEKECSSFQRAVNKILWIVGTARNAILVVVCCIMGYMLHTEEHGAP 323
            |:::|:..:.|:            ..|:..:...:.:      .::|||...:............
Mouse   311 CLLVLVPSKELN------------EHFKDKLKAPIPV------ELIVVVAATLASHFGKLNGNYN 357

  Fly   324 FRVVGEIPPGLPSIQLPPTSLTANETSNGVAEGFVEMVHSMGSGLVVIPLISLMENIAICKAFA- 387
            ..:.|.||.|....:.|..||..|...:.:|                |.:|.....:::.:.||
Mouse   358 SSIAGHIPTGFMPPKAPDWSLIPNVAVDAIA----------------ISIIGFAITVSLSEMFAK 406

  Fly   388 -NGKPVDASQELIAIGTANIFNSFVQAFPGTGALSRGAVNNASGVRTPLSNIYSGGLVMIALLFL 451
             :|..|.|:||:.|||..||..||......:.||::..|..::|.:|.||.|.:..::::.||.:
Mouse   407 KHGYTVKANQEMYAIGFCNIIPSFFHCITTSAALAKTLVKESTGCQTQLSAIVTALVLLLVLLVI 471

  Fly   452 TPYFYFIPRPTLAAI-IISAVVFMIEVKVVKPMWRSKKSDLVPGVGTFVACLVLPLEWGILIGVG 515
            .|.||.:.:..|..| |::....:::.:.:..|||..:.|.|....|.::..:|..|.|:|:||.
Mouse   472 APLFYSLQKCVLGVITIVNLRGALLKFRDLPKMWRLSRMDTVIWFVTMLSSALLSTEIGLLVGVC 536

  Fly   516 LNVIFILYHAARPKLSTELLTTQSGVEYSMITPDRCLIFPSVDYVRNLVNKQSIR 570
            .::..::....:||.|  ||    |:|....|      |.|:...:||.:|..|:
Mouse   537 FSMFCVILRTQKPKNS--LL----GLEEESET------FESISTYKNLRSKSGIK 579

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Esp	NP_001189282.1	sulP	86..615	CDD:273284	131/532 (25%)
		HCO3_cotransp	103..520	CDD:304903	108/462 (23%)
		STAS_SulP_like_sulfate_transporter	545..623	CDD:132913	7/26 (27%)
Slc26a2	NP_031911.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..47
		sulP	94..715	CDD:273284	131/532 (25%)
		STAS	570..707	CDD:294402	4/10 (40%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0659
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000041
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X49
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.810