Protein Alignment Esp and slc26a3.3

DIOPT Version :10

• Sequence 1: NP_524490.2
• Gene: Esp / 42962
• FlyBaseID: FBgn0013953
• Length: 654
• Species: Drosophila melanogaster
• Sequence 2: XP_031754872.1
• Gene: slc26a3.3 / 101731072
• XenbaseID: XB-GENE-22062173
• Length: 775
• Species: Xenopus tropicalis
• Alignment Length: 773
• Identity: 169/773 - (21%)
• Similarity: 309/773 - (39%)
• Gaps: 202/773 - (26%)

  Fly    36 SVGSQ-------GSKEFILTEDGKKVKPTVSTLDCTRSWLQDCQRRTFNRKTLHKRLPILGWLPK 93
            :||:|       .|:....||..|..:...:.||..|.:. .|.|....| ..:...||..|||.
 Frog     4 TVGNQYVVSRPIYSENAFHTEHEKLHRYHKTFLDHLRVFF-GCSREKAKR-IAYTFFPIASWLPM 66

  Fly    94 YNSQD-AVGDLVAGITVGLTVIPQALAYAGIAGLPVAYGLYASFVGCFVYIFLGSCKDVPMGPSA 157
            |..:: .:.|:|:||:.||..:.|.||:|.:..:...|||||:|.....|.|.|:.:.:.:||..
 Frog    67 YRFKEWILSDIVSGISTGLVAVLQGLAFALLVNVTPGYGLYAAFFPVITYFFFGTSRHISVGPFP 131

  Fly   158 IVALLTYQA------------AQGSWQKSVL----------LCLLSGIVELLMGLFGLGFLIDFV 200
            :::|:...|            |..:...::|          :.:|:||.:|.|||..:||::.::
 Frog   132 VLSLMVGTAVLRLAPDDPSISANNTEALTMLNEKRVVVAASVTVLAGIFQLAMGLLQIGFIVIYL 196

  Fly   201 SGPVSSGFTSAVSLIILTSQIQSVLGI-------------TAKGNTFVEIWTQVFHNIEHTRAGD 252
            |..:.||||:|.::.:|.||::.|.|:             |.||         :|..|..|...|
 Frog   197 SDSLISGFTTAAAIHVLVSQLKFVFGLKVEPFSGPLSLFYTLKG---------IFIQITDTNIAD 252

  Fly   253 TVLGLTCIVILLLMRSLSSCRIGPVDEKECSSFQRAVNKILWIVGTARNAILVVVCCIMGYMLHT 317
            .|..:..:|::.:::.::               .|...||  .|......|:.|:...:.|.|:.
 Frog   253 LVTSIIIMVVVFVVKEIN---------------DRFKAKI--PVPIPIEVIMTVIATGVSYALNF 300

  Fly   318 EEHGAPFRV--VGEIPPGLPSIQLPPTSLTANETSNGVAEGFVEMVHSMGSGLVVIPLISLMENI 380
            ::.   ::|  ||.:..|..    ||.:.:.:...:.|.:||            .|.::......
 Frog   301 KDR---YKVDIVGTLEKGFQ----PPIAPSLSVFQDCVGDGF------------SIAIVGFAVAF 346

  Fly   381 AICKAFA--NGKPVDASQELIAIGTANIFNSFVQAFPGTGALSRGAVNNASGVRTPLSNIYSGGL 443
            ::.|.::  :...::.:|||:|.|.:|||....:.|..:.||||.||..::|.:|.::.|.|..:
 Frog   347 SVAKVYSVKHDYVINGNQELVAFGLSNIFGGCFKGFAASTALSRSAVQESTGGKTQIAGILSAII 411

  Fly   444 VMIALLFLTPYFYFIPRPTLAA-IIISAVVFMIEVKVVKPMWRSKKSDLVPGVGTFVACLVLPLE 507
            |||.:|.:......:.:..|.| :||:....:::...:..::|..|.|::..:.||:..::|.|:
 Frog   412 VMIVILAIGFLIEPLQKSVLGALVIINLKGMLMQFNELPVLFRKDKYDMLVWIVTFLGAVLLGLD 476

  Fly   508 WGILIGVGLNVIFILYHAARPKLSTELLTTQSGV-----EYSMI-TPD-----RC---LIFPSVD 558
            .|:..|||..::.:::.|..||.|.......|.:     :|..| .|.     ||   :.|.:::
 Frog   477 LGLAAGVGFELLTVVFRAQFPKCSQIANVGGSNIYKNRKDYKNIYEPQGVKIFRCPSPVFFANIE 541

  Fly   559 Y--------------------------VRNLVNKQSIRQNVPVVI-------------DASHVYG 584
            :                          :|.|::|..::.....:|             |.:|:..
 Frog   542 FFKDKVIAAVGFNPLRILRKRNKALRKIRKLLSKGELQWTPKGMINTSNYNIDSDEELDNNHIEE 606

  Fly   585 ADFTTATV----------------------IDSLISDFNQ------------RGQLLFFYNLKPS 615
            .|..|.|.                      |.|||.||..            :|.|..|..::..
 Frog   607 LDQPTYTADLPITINWNEDLPNNISVPKIDIHSLILDFGAVSFIDMSGMKGLKGALKEFLKIEVD 671

  Fly   616 I---------------CSIF-EHVSAAQFVVYYQEQQLDELLKERNYVQ----KRLET 653
            |               |..| :.::.:...:...:..|..|.|:.|...    |..||
 Frog   672 IYIAGIDDNLLEKLERCGFFDDEITTSIIFLSIHDAVLHILAKKDNMANLNNFKEKET 729

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Esp	NP_524490.2	SUL1	93..622	CDD:440424	144/672 (21%)
slc26a3.3	XP_031754872.1	Sulfate_transp	73..466	CDD:459995	103/437 (24%)
		STAS_SulP_like_sulfate_transporter	517..693	CDD:132913	27/175 (15%)