DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Esp and slc26a5

DIOPT Version :9

Sequence 1:	NP_001189282.1	Gene:	Esp / 42962	FlyBaseID:	FBgn0013953	Length:	654	Species:	Drosophila melanogaster
Sequence 2:	XP_002933151.3	Gene:	slc26a5 / 100497573	XenbaseID:	XB-GENE-1000032	Length:	754	Species:	Xenopus tropicalis

Alignment Length:	513	Identity:	145/513 - (28%)
Similarity:	249/513 - (48%)	Gaps:	99/513 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    69 QDCQRRTFNRKT-LHKRLPILGWLPKYNSQD-AVGDLVAGITVGLTVIPQALAYAGIAGLPVAYG 131
            |.|:..:...|: |:..:|||.|||:|..:: .:||:::|::.|:..:||.||||.:||:|..||
Frog    49 QSCRCTSKKAKSQLYSFIPILKWLPRYPVKEYLLGDVISGLSTGVMQLPQGLAYALLAGVPPVYG 113

  Fly   132 LYASFVGCFVYIFLGSCKDVPMGPSAIVALL--------------TYQAAQGSWQKS-------- 174
            ||:||...|:|.|.||.:.:.:|..|:::|:              ....|.|:....
Frog   114 LYSSFYPVFLYTFFGSSRHISIGTFAVISLMIGGVAVRIAPDEMFDIMPANGTNSTDFDEKIEAR 178

  Fly   175 --------VLLCLLSGIVELLMGLFGLGFLIDFVSGPVSSGFTSAVSLIILTSQIQSVLGITAKG 231
                    |.|.|||||::|.:|:...||:..:::.|:..|||:|.::.:.|||::.:||:..|
Frog   179 DAMRVKVVVALTLLSGIIQLCLGILRFGFVAIYLTEPLVRGFTTAAAVHVFTSQLKYLLGVKTK- 242

  Fly   232 NTFVE------IWTQVFHNIEHTRAGDTVLGLTCIVILLLMRSLSSCRIGPVDEKECSSFQRAVN 290
             .|.|      .:..|..||........:|||:||::||..:.::            ..|::.:.
Frog   243 -RFREPLAVIFSFAAVLSNIMTVNVATLILGLSCILLLLGAKEIN------------DRFKKKLP 294

  Fly   291 KILWIVGTARNAILVVVCCIMGYMLHTEEHGAPFRVVGEI-----PPGLPSIQLPPTSLTANETS 350
                 |......|:|:|...:...|:.||..| ..|||:|     |||||.|.|
Frog   295 -----VPIPMEIIVVIVSTGVSAGLNLEESHA-VAVVGKIPTGFSPPGLPDITL----------- 342

  Fly   351 NGVAEGFVEMVHSMGSGLVVIPLISLMENIAICKAFA--NGKPVDASQELIAIGTANIFNSFVQA 413
              ..|.||:        .|.|.::.....|::.|.||  :|..|..:|||||:|..|...||.|.
Frog   343 --FKEVFVD--------AVAIAIVGFSMTISMAKIFALKHGYEVSGNQELIALGVCNSVGSFFQT 397

  Fly   414 FPGTGALSRGAVNNASGVRTPLSNIYSGGLVMIALLFLTPYFYFIPRPTLAAIIISAVVFMIEVK 478
            |..|.::||..|..::|..|.::.:.|..:|::.::.:...|..:|:..||||:      |:.:|
Frog   398 FSVTCSMSRSLVQESTGGNTQIAGLLSSLMVLLVIVVIGYLFQPLPQTVLAAIV------MVNLK 456

  Fly   479 -------VVKPMWRSKKSDLVPGVGTFVACLVLPLEWGILIGVGLNVIFILYHAARPK 529
                   .:..:||:.:.:|...|.:|:|.:.|.|::|:|:.|...::.::|....|:
Frog   457 GMFKQFADIPHLWRTSRLELSIWVVSFLASVSLGLDYGLLVAVTFAILTVIYRTQSPQ 514

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Esp	NP_001189282.1	sulP	86..615	CDD:273284	141/495 (28%)
		HCO3_cotransp	103..520	CDD:304903	130/466 (28%)
		STAS_SulP_like_sulfate_transporter	545..623	CDD:132913
slc26a5	XP_002933151.3	sulP	67..725	CDD:273284	141/495 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000041
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X49
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.000