Protein Alignment Esp and slc26a10

DIOPT Version :10

• Sequence 1: NP_524490.2
• Gene: Esp / 42962
• FlyBaseID: FBgn0013953
• Length: 654
• Species: Drosophila melanogaster
• Sequence 2: XP_001921766.4
• Gene: slc26a10 / 100150270
• ZFINID: ZDB-GENE-030131-9845
• Length: 690
• Species: Danio rerio
• Alignment Length: 707
• Identity: 172/707 - (24%)
• Similarity: 305/707 - (43%)
• Gaps: 155/707 - (21%)

  Fly    46 ILTEDGKKVKPTVSTLDCT--RSWLQD--CQRRTFNR----KTLHKRLPILGWLPKYNSQD-AVG 101
            |.|||  :.:.|..|.|.:  |..|:|  .||.:.::    ..||||||:..|||||..:. .:|
Zfish    11 IYTED--RFRQTYGTEDQSGGRERLRDRLAQRCSCSQVECVHLLHKRLPVCSWLPKYKLRKWLLG 73

  Fly   102 DLVAGITVGLTVIPQALAYAGIAGLPVAYGLYASFVGCFVYIFLGSCKDVPMGPSAIVALLT--- 163
            |::||:|||:..|||.:|:|.:..:...||||.||....:|:..|:...|..|..|:::|:|
Zfish    74 DIIAGLTVGIVHIPQGMAFALLTSVAPVYGLYTSFFPVVLYMLFGTGHHVSTGTFAVLSLMTGSV 138

  Fly   164 ---------------YQAAQGSWQK---SVLLCLLSGIVELLMGLFGLGFLIDFVSGPVSSGFTS 210
                           .:||:...|:   :..:..||||:.|.|....||||..::|.|:...|||
Zfish   139 VEQLVPIPLALNSSSPEAAEFEAQRIGVASAVAFLSGIMMLCMCGLQLGFLSTYLSEPIVKAFTS 203

  Fly   211 AVSLIILTSQIQSVLGIT----AKGNTFVEIWTQVFHNIEHTRAGDTVLGLTCIVILLLMRSLSS 271
            |.:..:..||:||:||:.    |...:..:....|..|:.||...:.|:.|.|:.:|:
Zfish   204 AAAFHVTVSQLQSMLGLRLPRYAGAFSLFKTLASVMENVPHTNLAELVISLLCLAVLV------- 261

  Fly   272 CRIGPVDEKECSSFQRAVNKILWIVGTARNAILVVVCCIMGYMLHTEEHGAPFRVVGEIPPGLPS 336
                ||.|.. |.|:..:...:.:     ..|.|::...:.|....:.. ...::||.||.|.|.
Zfish   262 ----PVKEVN-SRFRERLRTPIPV-----EIITVIIATGITYAFSLDSK-YDIQIVGHIPAGFPE 315

  Fly   337 IQLPPTSLTANETSNGVAEGFVEMVHSMGSGLVVIPLISLMENIAICKAFA--NGKPVDASQELI 399
            .:||.                :|.|..:....|.|.|::...::::...:|  :|..:|.:|||:
Zfish   316 PRLPA----------------LETVPEIAGDTVAITLVAYAVSVSLAMIYADKHGYSIDPNQELL 364

  Fly   400 AIGTANIFNSFVQAFPGTGALSRGAVNNASGVRTPLSNIYSGGLVMIALLFLTPYFYFIPRPTLA 464
            |.|.:|..:|....||.:..|:...:..::|..|.|:.:::..:|:|.||.:.|.|||:|:..||
Zfish   365 AHGISNTVSSLFTCFPNSATLATTNILESAGGHTQLAGLFTSLVVLIVLLLIGPLFYFLPKAVLA 429

  Fly   465 AIIISAVVFM-IEVKVVKPMWRSKKSDLVPGVGTFVACLVLPLEWGILIGVGLNVIFILYHAARP 528
            .|.::::..| ::.:.:..:||..|.|.:..:.|:::.:||.::.|:.||:..:::.::....|.
Zfish   430 CINVTSLRQMFLQFQDLPELWRISKIDFMVWLVTWLSVVVLNVDLGLAIGMVFSMMTVVCRTQRA 494

  Fly   529 KLS-------------------------TELLTTQSGVEYSM-------------ITPDRCLIFP 555
            ..|                         .::||....:.|..             :||:|   ..
Zfish   495 SCSVLGRAANTEIYRSINNHNKCYEVPGVKILTYNGPIYYGNRSFFKADMAQLLGLTPER---IR 556

  Fly   556 SVDYVRNLVNKQ------SIRQNV----------------------PVVIDASHVYGADFTTATV 592
            |.:.....:.|:      ::.|.|                      .|:||.|.|...|...|.:
Zfish   557 SREKALKAIEKREREAISTVEQGVADSSFSSKNDLFTSEMAEGEVQAVLIDCSSVIFVDIAGARL 621

  Fly   593 IDSLISDFNQRGQLLFFYNLKPSICSIF-----------EH--VSAAQFVVYYQEQQ 636
            ...:..:..:.|..::..|...|:..|.           :|  |:....|||.|:|:
Zfish   622 FIQMCMECQKIGVRIYLANCNESVLKILTSSGLMNYMNPQHIFVTIHDAVVYIQQQR 678

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Esp	NP_524490.2	SUL1	93..622	CDD:440424	144/634 (23%)
slc26a10	XP_001921766.4	PRK11660	57..670	CDD:481320	150/649 (23%)