Protein Alignment Esp and slc26a6

DIOPT Version :9

• Sequence 1: NP_001189282.1
• Gene: Esp / 42962
• FlyBaseID: FBgn0013953
• Length: 654
• Species: Drosophila melanogaster
• Sequence 2: XP_001344243.4
• Gene: slc26a6 / 100005108
• ZFINID: ZDB-GENE-081105-83
• Length: 747
• Species: Danio rerio
• Alignment Length: 609
• Identity: 141/609 - (23%)
• Similarity: 273/609 - (44%)
• Gaps: 116/609 - (19%)

  Fly    85 LPILGWLPKYN-SQDAVGDLVAGITVGLTVIPQALAYAGIAGLPVAYGLYASFVGCFVYIFLGSC 148
            :|:|.|||||. .::|:|||::||:||:..:||.:|||.:|.:|..:|||:||....:|...|:.
Zfish    62 IPLLAWLPKYPFRENAIGDLISGISVGIMHLPQGMAYALLAAVPPVFGLYSSFYPILIYFIFGTS 126

  Fly   149 KDVPMGPSAIVALLTYQAAQ-----------GSWQKSVLL----------------CLLSGIVEL 186
            |.:.:|..|:::::.....:           |:...|..:                ..||||.:|
Zfish   127 KHISVGTYAVMSVMIGSVTERLAPDSDFTFPGNETNSTYIDFSSRDAERVKIAATVTFLSGIFQL 191

  Fly   187 LMGLFGLGFLIDFVSGPVSSGFTSAVSLIILTSQIQSVLGITAKG--------NTFVEIWTQVFH 243
            |:|:...||::.::|.|:...:|:|.::.::.||::...||....        .|.:||...
Zfish   192 LLGVVRFGFVVTYLSEPLVRSYTTAAAIHVIVSQLKYSFGINPHRYSGPLSLIYTVIEICAL--- 253

  Fly   244 NIEHTRAGDTVLGLTCIVILLLMRSLSSCRIGPVDEKECSSFQRAVNKILWIVGTARNAILVVVC 308
             :..|..|..|:.:..||.|::.:.||:.               |..||  .:......|.:::.
Zfish   254 -LGKTNIGTLVVSIVTIVGLIIAKELSAL---------------AAKKI--PIPIPVELITIIIA 300

  Fly   309 CIMGYMLHTEEHGAPFRVVGEIPPGLPSIQLPPTSLTANETSNGVAEGFVEMVHSMGSGLVVIPL 373
            .::.:.:..:.. ....||||||.||.:    |.:...::..:.|.:.|...|  :|.|:.
Zfish   301 TVVSWYMDLKTI-YKVEVVGEIPSGLQA----PVAPKVSQLGSMVGDAFALAV--VGYGIA---- 354

  Fly   374 ISLMENIAICKAFANGKPVDASQELIAIGTANIFNSFVQAFPGTGALSRGAVNNASGVRTPLSNI 438
            |||....|:..|:    .||::|||||:|.:|........|..:.::||..|..::|.::.::..
Zfish   355 ISLGRIFALKYAY----KVDSNQELIALGLSNSIGGLFSCFAISCSMSRSMVQVSTGGKSQVAGA 415

  Fly   439 YSGGLVMIALLFLTPYFYFIPRPTLAAII-ISAVVFMIEVKVVKPMWRSKKSDLVPGVGTFVACL 502
            .|..::::.||.:...|..:|:..||||| ::....|.:...:..:||:.|.|:|..|.|.:..:
Zfish   416 ISALVILVILLKIGELFEELPKAVLAAIIYVNLQGMMKQFGDICSLWRTNKVDMVVWVMTMILTI 480

  Fly   503 VLPLEWGILIGVGLNVIFILYHAARPKLSTELLTTQSGVEYSMITPDRCLIFPSVDYVRNLVNKQ 567
            :...:.|:...:..:::.:::....||             ||::..     .|..|..:.:.:..
Zfish   481 LFNPDMGLAASIAFSILTVVFRTQLPK-------------YSILGQ-----IPGTDIYKPVEDYN 527

  Fly   568 SIRQNVPVVIDASHVYGADFTTATVIDSLISDFNQRGQLLFFYNLKPSICSIFEH--VSAAQFVV 630
            .:::...:.|..|        :||               |:|.|.:..|.:::|.  |..|:.:.
Zfish   528 QVKEIPGITIFRS--------SAT---------------LYFANAEMYIDALYEKTGVDVAKLLS 569

  Fly   631 YYQEQQLDELLKERNYVQKRLETA 654
            :.::.|...|.||:...:|..:.|
Zfish   570 HKKKLQAKRLRKEKKAAKKAKKEA 593

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Esp	NP_001189282.1	sulP	86..615	CDD:273284	131/565 (23%)
		HCO3_cotransp	103..520	CDD:304903	108/452 (24%)
		STAS_SulP_like_sulfate_transporter	545..623	CDD:132913	11/79 (14%)
slc26a6	XP_001344243.4	sulP	63..729	CDD:273284	141/608 (23%)
		STAS_SulP_like_sulfate_transporter	<655..725	CDD:132913

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0659
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000041
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100144
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1414
SonicParanoid	1	1.000	-	-		X49
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	6	5.740