Protein Alignment RabX4 and RAB28

DIOPT Version :10

• Sequence 1: NP_733043.1
• Gene: RabX4 / 42960
• FlyBaseID: FBgn0051118
• Length: 213
• Species: Drosophila melanogaster
• Sequence 2: NP_001017979.1
• Gene: RAB28 / 9364
• HGNCID: 9768
• Length: 221
• Species: Homo sapiens
• Alignment Length: 200
• Identity: 57/200 - (28%)
• Similarity: 93/200 - (46%)
• Gaps: 18/200 - (9%)

  Fly    10 KVLVLGDSNVGKTCIVHRYCDEKYYDTYISTIGIDFKQKLINLDG-VPIKLQIWDTAGQERFRTL 73
            |::||||...|||.:...:..|.:...|..|||:||..:.|.|.| :.:.|||||..||.....:
Human    14 KIVVLGDGASGKTSLTTCFAQETFGKQYKQTIGLDFFLRRITLPGNLNVTLQIWDIGGQTIGGKM 78

  Fly    74 TTAYYRGAMGILLMYDVTNLESYNNLSYW---LRNIQENASPDVVKVLAGNKCECSATQRMVDKE 135
            ...|..||.|:||:||:||.:|:.||..|   ::.:.|.:....:..|.|||.:.. ..|.:..|
Human    79 LDKYIYGAQGVLLVYDITNYQSFENLEDWYTVVKKVSEESETQPLVALVGNKIDLE-HMRTIKPE 142

  Fly   136 RGEKIAENFDMPFFEVSCKSNINIEDAFLSLARKI-----------REQRERRGD--NFDNDESK 187
            :..:..:........||.|:..::...|..:|.:|           :.||..:.|  |::.:...
Human   143 KHLRFCQENGFSSHFVSAKTGDSVFLCFQKVAAEILGIKLNKAEIEQSQRVVKADIVNYNQEPMS 207

  Fly   188 DKKSP 192
            ...:|
Human   208 RTVNP 212

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RabX4	NP_733043.1	RAB	9..170	CDD:197555	51/163 (31%)
RAB28	NP_001017979.1	Rab28	13..221	CDD:206694	56/199 (28%)
		Switch I. /evidence=ECO:0000255|PROSITE-ProRule:PRU00753, ECO:0000269|PubMed:19026641, ECO:0007744|PDB:3E5H	35..49		5/13 (38%)
		Switch II. /evidence=ECO:0000255|PROSITE-ProRule:PRU00753, ECO:0000269|PubMed:19026641, ECO:0007744|PDB:3E5H	68..85		4/16 (25%)