Protein Alignment RabX4 and RAB1B

DIOPT Version :10

• Sequence 1: NP_733043.1
• Gene: RabX4 / 42960
• FlyBaseID: FBgn0051118
• Length: 213
• Species: Drosophila melanogaster
• Sequence 2: NP_112243.1
• Gene: RAB1B / 81876
• HGNCID: 18370
• Length: 201
• Species: Homo sapiens
• Alignment Length: 165
• Identity: 83/165 - (50%)
• Similarity: 126/165 - (76%)
• Gaps: 1/165 - (0%)

  Fly     9 YKVLVLGDSNVGKTCIVHRYCDEKYYDTYISTIGIDFKQKLINLDGVPIKLQIWDTAGQERFRTL 73
            :|:|::|||.|||:|::.|:.|:.|.::||||||:|||.:.|.|||..||||||||||||||||:
Human     9 FKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQERFRTI 73

  Fly    74 TTAYYRGAMGILLMYDVTNLESYNNLSYWLRNIQENASPDVVKVLAGNKCECSATQRMVDKERGE 138
            |::|||||.||:::||||:.|||.|:..||:.|...||.:|.|:|.|||.:.: |:::||....:
Human    74 TSSYYRGAHGIIVVYDVTDQESYANVKQWLQEIDRYASENVNKLLVGNKSDLT-TKKVVDNTTAK 137

  Fly   139 KIAENFDMPFFEVSCKSNINIEDAFLSLARKIREQ 173
            :.|::..:||.|.|.|:..|:|.||:::|.:|:::
Human   138 EFADSLGIPFLETSAKNATNVEQAFMTMAAEIKKR 172

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RabX4	NP_733043.1	RAB	9..170	CDD:197555	82/160 (51%)
RAB1B	NP_112243.1	Rab1_Ypt1	7..172	CDD:206661	83/163 (51%)
		Switch 1. /evidence=ECO:0000269|PubMed:20064470, ECO:0007744|PDB:3JZA	30..45		8/14 (57%)
		Switch 2 region, required for interaction with REP1/CHM	64..83		15/18 (83%)
		Switch 2. /evidence=ECO:0000269|PubMed:20064470, ECO:0007744|PDB:3JZA	65..80		11/14 (79%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	174..201