DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment RabX4 and Rab35

DIOPT Version :9

Sequence 1:	NP_733043.1	Gene:	RabX4 / 42960	FlyBaseID:	FBgn0051118	Length:	213	Species:	Drosophila melanogaster
Sequence 2:	NP_937806.1	Gene:	Rab35 / 77407	MGIID:	1924657	Length:	201	Species:	Mus musculus

Alignment Length:	200	Identity:	78/200 - (39%)
Similarity:	125/200 - (62%)	Gaps:	12/200 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MALDFVATYKVLVLGDSNVGKTCIVHRYCDEKYYDTYISTIGIDFKQKLINLDGVPIKLQIWDTA 65
            ||.|:...:|:|::|||.|||:.::.|:.|..:..:||:|||:|||.:.:.::|..:||||||||
Mouse     1 MARDYDHLFKLLIIGDSGVGKSSLLLRFADNTFSGSYITTIGVDFKIRTVEINGEKVKLQIWDTA 65

  Fly    66 GQERFRTLTTAYYRGAMGILLMYDVTNLESYNNLSYWLRNIQENASPDVVKVLAGNKCECSATQR 130
            |||||||:|:.||||..|::::||||:.||:.|:..||..|.:|.. ||.::|.|||.: ...::
Mouse    66 GQERFRTITSTYYRGTHGVIVVYDVTSAESFVNVKRWLHEINQNCD-DVCRILVGNKND-DPERK 128

  Fly   131 MVDKERGEKIAENFDMPFFEVSCKSNINIEDAFLSLARKI---------REQRERRGDNFD-NDE 185
            :|:.|...|.|....:..||.|.|.|:|:|:.|..:...:         ::|::::.|... ...
Mouse   129 VVETEDAYKFAGQMGIQLFETSAKENVNVEEMFNCITELVLRAKKDNLAKQQQQQQNDVVKLTKN 193

  Fly   186 SKDKK 190
            ||.||
Mouse   194 SKRKK 198

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
RabX4	NP_733043.1	RAB	9..170	CDD:197555	69/160 (43%)
Rab35	NP_937806.1	Rab35	3..201	CDD:133310	75/197 (38%)
Rab35	NP_937806.1	Effector region. /evidence=ECO:0000250	37..45		5/7 (71%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910