Protein Alignment RabX4 and RAB5A

DIOPT Version :10

• Sequence 1: NP_733043.1
• Gene: RabX4 / 42960
• FlyBaseID: FBgn0051118
• Length: 213
• Species: Drosophila melanogaster
• Sequence 2: NP_004153.2
• Gene: RAB5A / 5868
• HGNCID: 9783
• Length: 215
• Species: Homo sapiens
• Alignment Length: 190
• Identity: 64/190 - (33%)
• Similarity: 115/190 - (60%)
• Gaps: 15/190 - (7%)

  Fly     6 VATYKVLVLGDSNVGKTCIVHRYCDEKYYDTYISTIGIDFKQKLINLDGVPIKLQIWDTAGQERF 70
            :..:|:::||:|.|||:.:|.|:...::::...||||..|..:.:.||...:|.:|||||||||:
Human    18 ICQFKLVLLGESAVGKSSLVLRFVKGQFHEFQESTIGAAFLTQTVCLDDTTVKFEIWDTAGQERY 82

  Fly    71 RTLTTAYYRGAMGILLMYDVTNLESYNNLSYWLRNIQENASPDVVKVLAGNKCECSATQRMVDKE 135
            .:|...|||||...:::||:||.||:.....|::.:|..|||::|..|:|||.:. |.:|.||.:
Human    83 HSLAPMYYRGAQAAIVVYDITNEESFARAKNWVKELQRQASPNIVIALSGNKADL-ANKRAVDFQ 146

  Fly   136 RGEKIAENFDMPFFEVSCKSNINIEDAFLSLARKIREQRERRGDNFDNDESKDKKSPGSN 195
            ..:..|::..:.|.|.|.|:::|:.:.|:::|:|:              ...:.::||:|
Human   147 EAQSYADDNSLLFMETSAKTSMNVNEIFMAIAKKL--------------PKNEPQNPGAN 192

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RabX4	NP_733043.1	RAB	9..170	CDD:197555	60/160 (38%)
RAB5A	NP_004153.2	Rab5_related	20..182	CDD:206653	61/176 (35%)
		Switch 1. /evidence=ECO:0000269|PubMed:20534488, ECO:0007744|PDB:3MJH	44..56		4/11 (36%)
		Switch 2. /evidence=ECO:0000269|PubMed:20534488, ECO:0007744|PDB:3MJH	77..93		9/15 (60%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	181..215		3/26 (12%)