Protein Alignment RabX4 and RAB3A

DIOPT Version :10

• Sequence 1: NP_733043.1
• Gene: RabX4 / 42960
• FlyBaseID: FBgn0051118
• Length: 213
• Species: Drosophila melanogaster
• Sequence 2: NP_002857.1
• Gene: RAB3A / 5864
• HGNCID: 9777
• Length: 220
• Species: Homo sapiens
• Alignment Length: 189
• Identity: 84/189 - (44%)
• Similarity: 120/189 - (63%)
• Gaps: 1/189 - (0%)

  Fly     4 DFVATYKVLVLGDSNVGKTCIVHRYCDEKYYDTYISTIGIDFKQKLINLDGVPIKLQIWDTAGQE 68
            :|...:|:|::|:|:||||..:.||.|:.:...::||:|||||.|.|..:...||||||||||||
Human    18 NFDYMFKILIIGNSSVGKTSFLFRYADDSFTPAFVSTVGIDFKVKTIYRNDKRIKLQIWDTAGQE 82

  Fly    69 RFRTLTTAYYRGAMGILLMYDVTNLESYNNLSYWLRNIQENASPDVVKVLAGNKCECSATQRMVD 133
            |:||:||||||||||.:||||:||.||:|.:..|...|:..:..:...:|.||||:.. .:|:|.
Human    83 RYRTITTAYYRGAMGFILMYDITNEESFNAVQDWSTQIKTYSWDNAQVLLVGNKCDME-DERVVS 146

  Fly   134 KERGEKIAENFDMPFFEVSCKSNINIEDAFLSLARKIREQRERRGDNFDNDESKDKKSP 192
            .|||.::|::....|||.|.|.|||::..|..|...|.|:.....|..|...:..|:.|
Human   147 SERGRQLADHLGFEFFEASAKDNINVKQTFERLVDVICEKMSESLDTADPAVTGAKQGP 205

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RabX4	NP_733043.1	RAB	9..170	CDD:197555	77/160 (48%)
RAB3A	NP_002857.1	Rab3	22..186	CDD:206657	78/164 (48%)
		Switch 1. /evidence=ECO:0000250|UniProtKB:P63012	49..58		3/8 (38%)
		Switch 2. /evidence=ECO:0000250|UniProtKB:P63012	80..96		13/15 (87%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	194..220		3/12 (25%)