Protein Alignment RabX4 and RAB2A

DIOPT Version :10

• Sequence 1: NP_733043.1
• Gene: RabX4 / 42960
• FlyBaseID: FBgn0051118
• Length: 213
• Species: Drosophila melanogaster
• Sequence 2: NP_002856.1
• Gene: RAB2A / 5862
• HGNCID: 9763
• Length: 212
• Species: Homo sapiens
• Alignment Length: 200
• Identity: 73/200 - (36%)
• Similarity: 130/200 - (65%)
• Gaps: 1/200 - (0%)

  Fly     9 YKVLVLGDSNVGKTCIVHRYCDEKYYDTYISTIGIDFKQKLINLDGVPIKLQIWDTAGQERFRTL 73
            :|.:::||:.|||:|::.::.|:::...:..|||::|..::|.:||..||||||||||||.||::
Human     7 FKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQIKLQIWDTAGQESFRSI 71

  Fly    74 TTAYYRGAMGILLMYDVTNLESYNNLSYWLRNIQENASPDVVKVLAGNKCECSATQRMVDKERGE 138
            |.:|||||.|.||:||:|..:::|:|:.||.:.:::::.::|.:|.|||.:.. ::|.|.||.||
Human    72 TRSYYRGAAGALLVYDITRRDTFNHLTTWLEDARQHSNSNMVIMLIGNKSDLE-SRREVKKEEGE 135

  Fly   139 KIAENFDMPFFEVSCKSNINIEDAFLSLARKIREQRERRGDNFDNDESKDKKSPGSNGLGTFSLG 203
            ..|....:.|.|.|.|:..|:|:||::.|::|.|:.:....:.:|:.:..|..|..........|
Human   136 AFAREHGLIFMETSAKTASNVEEAFINTAKEIYEKIQEGVFDINNEANGIKIGPQHAATNATHAG 200

  Fly   204 SLSGE 208
            :..|:
Human   201 NQGGQ 205

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RabX4	NP_733043.1	RAB	9..170	CDD:197555	66/160 (41%)
RAB2A	NP_002856.1	PLN03108	1..188	CDD:178655	70/181 (39%)
		Required for interaction with PRKCI. /evidence=ECO:0000269|PubMed:14570876	2..19		4/11 (36%)
		Switch 1. /evidence=ECO:0000250|UniProtKB:P61106	37..42		3/4 (75%)
		Switch 2. /evidence=ECO:0000250|UniProtKB:P61106	63..72		6/8 (75%)