Protein Alignment RabX4 and RAB14

DIOPT Version :10

• Sequence 1: NP_733043.1
• Gene: RabX4 / 42960
• FlyBaseID: FBgn0051118
• Length: 213
• Species: Drosophila melanogaster
• Sequence 2: NP_057406.2
• Gene: RAB14 / 51552
• HGNCID: 16524
• Length: 215
• Species: Homo sapiens
• Alignment Length: 205
• Identity: 79/205 - (38%)
• Similarity: 122/205 - (59%)
• Gaps: 1/205 - (0%)

  Fly     9 YKVLVLGDSNVGKTCIVHRYCDEKYYDTYISTIGIDFKQKLINLDGVPIKLQIWDTAGQERFRTL 73
            :|.:::||..|||:|::|::.::|:......|||::|..::|.:.|..|||||||||||||||.:
Human    12 FKYIIIGDMGVGKSCLLHQFTEKKFMADCPHTIGVEFGTRIIEVSGQKIKLQIWDTAGQERFRAV 76

  Fly    74 TTAYYRGAMGILLMYDVTNLESYNNLSYWLRNIQENASPDVVKVLAGNKCECSATQRMVDKERGE 138
            |.:|||||.|.|::||:|...:||:||.||.:.:...:|:.|.:|.|||.:..| ||.|..|..:
Human    77 TRSYYRGAAGALMVYDITRRSTYNHLSSWLTDARNLTNPNTVIILIGNKADLEA-QRDVTYEEAK 140

  Fly   139 KIAENFDMPFFEVSCKSNINIEDAFLSLARKIREQRERRGDNFDNDESKDKKSPGSNGLGTFSLG 203
            :.||...:.|.|.|.|:..|:|||||..|:||.:..:....:.:..||..:..|.:...|..:..
Human   141 QFAEENGLLFLEASAKTGENVEDAFLEAAKKIYQNIQDGSLDLNAAESGVQHKPSAPQGGRLTSE 205

  Fly   204 SLSGENRCTC 213
            .......|.|
Human   206 PQPQREGCGC 215

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RabX4	NP_733043.1	RAB	9..170	CDD:197555	71/160 (44%)
RAB14	NP_057406.2	Rab14	10..175	CDD:133322	73/163 (45%)
		Switch 1. /evidence=ECO:0000269|PubMed:26032412, ECO:0007744|PDB:4D0G	42..47		3/4 (75%)
		Switch 2. /evidence=ECO:0000269|PubMed:26032412, ECO:0007744|PDB:4D0G	68..77		7/8 (88%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	188..215		4/26 (15%)