DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment RabX4 and RAB44

DIOPT Version :9

Sequence 1:	NP_733043.1	Gene:	RabX4 / 42960	FlyBaseID:	FBgn0051118	Length:	213	Species:	Drosophila melanogaster
Sequence 2:	NP_001244286.1	Gene:	RAB44 / 401258	HGNCID:	21068	Length:	1021	Species:	Homo sapiens

Alignment Length:	172	Identity:	67/172 - (38%)
Similarity:	103/172 - (59%)	Gaps:	1/172 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 YKVLVLGDSNVGKTCIVHRYCDEKYYDTYISTIGIDFKQKLINLDGVPIKLQIWDTAGQERFRTL 73
            :.|:.|||||||||..:|......:.....:|:|:||:.|.:.:|.....||:||||||||:.::
Human   834 FHVIFLGDSNVGKTSFLHLLHQNSFATGLTATVGVDFRVKTLLVDNKCFVLQLWDTAGQERYHSM 898

  Fly    74 TTAYYRGAMGILLMYDVTNLESYNNLSYWLRNIQENASPDVVKVLAGNKCECSATQRMVDKERGE 138
            |....|.|.|::||||:|:.||:.::.|||..:|:..|..||.:|.|||.:|. .:|.|..|.|:
Human   899 TRQLLRKADGVVLMYDITSQESFAHVRYWLDCLQDAGSDGVVILLLGNKMDCE-EERQVSVEAGQ 962

  Fly   139 KIAENFDMPFFEVSCKSNINIEDAFLSLARKIREQRERRGDN 180
            ::|:...:.|.|.|.....||.:..::|||.:|.|.|...|:
Human   963 QLAQELGVYFGECSAALGHNILEPVVNLARSLRMQEEGLKDS 1004

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
RabX4	NP_733043.1	RAB	9..170	CDD:197555	63/160 (39%)
RAB44	NP_001244286.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..40
		EF-hand_8	59..102	CDD:316358
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	113..133
		SMC_N	<191..>337	CDD:330553
		Atrophin-1	<326..647	CDD:331285
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	339..405
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	419..483
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	495..827
		DNA_pol3_gamma3	<523..831	CDD:331207
		Rab	834..992	CDD:206640	61/158 (39%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0078
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810