Protein Alignment RabX4 and RAB15

DIOPT Version :10

• Sequence 1: NP_733043.1
• Gene: RabX4 / 42960
• FlyBaseID: FBgn0051118
• Length: 213
• Species: Drosophila melanogaster
• Sequence 2: NP_001295083.1
• Gene: RAB15 / 376267
• HGNCID: 20150
• Length: 212
• Species: Homo sapiens
• Alignment Length: 226
• Identity: 81/226 - (35%)
• Similarity: 133/226 - (58%)
• Gaps: 27/226 - (11%)

  Fly     1 MALDFVATYKVLVLGDSNVGKTCIVHRYCDEKYYDTYISTIGIDFKQKLINLDGVPIKLQIWDTA 65
            ||..:...:::|::|||.|||||::.|:.|.:::.::|||||:|||.|.|.:||:.:::||||||
Human     1 MAKQYDVLFRLLLIGDSGVGKTCLLCRFTDNEFHSSHISTIGVDFKMKTIEVDGIKVRIQIWDTA 65

  Fly    66 GQERFRTLTTAYYRGAMGILLMYDVTNLESYNNLSYWLRNIQENASPDVVKVLAGNKCECSATQR 130
            ||||::|:|..|||.|.||.|:||:::..||.::..|:.::.|.|...|.|:|.|||.: ...:|
Human    66 GQERYQTITKQYYRRAQGIFLVYDISSERSYQHIMKWVSDVDEYAPEGVQKILIGNKAD-EEQKR 129

  Fly   131 MVDKERGEKIAENFDMPFFEVSCKSNINIEDAFLSLA-------RKIREQRERRGDN------FD 182
            .|.:|:|:::|:.:.|.|:|.|..:|:||:::|..|.       ||..|....|..|      .:
Human   130 QVGREQGQQLAKEYGMDFYETSACTNLNIKESFTRLTELVLQAHRKELEGLRMRASNELALAELE 194

  Fly   183 NDESKDKKSPGSNGLGTFSLGSLSGENRCTC 213
            .:|.|.:             |..:....|.|
Human   195 EEEGKPE-------------GPANSSKTCWC 212

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RabX4	NP_733043.1	RAB	9..170	CDD:197555	70/167 (42%)
RAB15	NP_001295083.1	Rab15	9..172	CDD:206698	69/163 (42%)
		Switch 1. /evidence=ECO:0000250|UniProtKB:P62820	31..45		5/13 (38%)
		Switch 2. /evidence=ECO:0000250|UniProtKB:P62820	63..80		11/16 (69%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	193..212		4/31 (13%)