DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment RabX4 and Rasef

DIOPT Version :9

Sequence 1:	NP_733043.1	Gene:	RabX4 / 42960	FlyBaseID:	FBgn0051118	Length:	213	Species:	Drosophila melanogaster
Sequence 2:	XP_006537989.1	Gene:	Rasef / 242505	MGIID:	2448565	Length:	708	Species:	Mus musculus

Alignment Length:	208	Identity:	70/208 - (33%)
Similarity:	118/208 - (56%)	Gaps:	16/208 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 YKVLVLGDSNVGKTCIVHRYCDEKYYDTYISTIGIDFKQKLINLDGVPIKLQIWDTAGQERFRTL 73
            ||:::.||:.|||:..:.|.|..::.....:|:|:||:.|.:.:||....||:||||||||||::
Mouse   510 YKIVLAGDAAVGKSSFLMRLCKNEFQGNTSATLGVDFQMKTLIVDGEQTVLQLWDTAGQERFRSI 574

  Fly    74 TTAYYRGAMGILLMYDVTNLESYNNLSYWLRNIQENASPDVVKVLAGNKCEC-----SATQRMVD 133
            ..:|:|.|.|:||:||||..:|:.|:..|:..:::.....:..:|.|||.:.     :..|:.:.
Mouse   575 AKSYFRKADGVLLLYDVTCEKSFLNVREWVDMVEDGTHRTIPIMLVGNKADLRDVDNAENQKCIS 639

  Fly   134 KERGEKIAENFDMPFFEVSCKSNINIEDAFLSLARKIREQRERRGDNFDNDESKDKKSPGSNGLG 198
            ...|||:|..:...|.|.|.|...|:.:|.|.|||:::::.|       :|:|:...|..    |
Mouse   640 AYLGEKLAMTYGALFCETSAKDGSNVVEAVLHLAREVKKRTE-------DDDSRSITSLA----G 693

  Fly   199 TFSLGSLSGENRC 211
            :.|..||..:|.|
Mouse   694 STSKKSLQMKNCC 706

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
RabX4	NP_733043.1	RAB	9..170	CDD:197555	60/165 (36%)
Rasef	XP_006537989.1	EFh	12..72	CDD:238008
		Smc	<108..339	CDD:224117
		Rab	510..674	CDD:206640	58/163 (36%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0078
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810