DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment RabX4 and rab-35

DIOPT Version :9

Sequence 1:	NP_733043.1	Gene:	RabX4 / 42960	FlyBaseID:	FBgn0051118	Length:	213	Species:	Drosophila melanogaster
Sequence 2:	NP_499454.1	Gene:	rab-35 / 176560	WormBaseID:	WBGene00004284	Length:	209	Species:	Caenorhabditis elegans

Alignment Length:	215	Identity:	86/215 - (40%)
Similarity:	130/215 - (60%)	Gaps:	17/215 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 DFVATYKVLVLGDSNVGKTCIVHRYCDEKYYDTYISTIGIDFKQKLINLDGVPIKLQIWDTAGQE 68
            |:...:|:|::|||.|||:.::.|:.|..:.:.||:|||:|||.:.::::|..:|||||||||||
Worm     6 DYDHLFKLLIIGDSGVGKSSLLLRFADNTFSENYITTIGVDFKIRTMDINGQRVKLQIWDTAGQE 70

  Fly    69 RFRTLTTAYYRGAMGILLMYDVTNLESYNNLSYWLRNIQENASPDVVKVLAGNKCECSATQRMVD 133
            ||||:|:.||||..|::::|||||.||:.|:..||:.|:.|.. .|.|||.||||| ...:|:|.
Worm    71 RFRTITSTYYRGTHGVVVVYDVTNGESFGNVKRWLQEIENNCD-SVQKVLVGNKCE-ENERRVVL 133

  Fly   134 KERGEKIAENFDMPFFEVSCKSNINIEDAF-----LSLARKIREQRERRGDNFDNDESKDKKSPG 193
            :......|::.::.|||.|.|.:.|:|..|     |.|..|:...:         ..|||:...|
Worm   134 ESDARNYAQSMNISFFETSAKEDKNVEPMFTCITSLVLTAKLANPQ---------SASKDQSRTG 189

  Fly   194 SNGLGTFSLGSLSGENRCTC 213
            ...|...| ||.:.:.:|.|
Worm   190 GVSLKDNS-GSTNQKKKCKC 208

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
RabX4	NP_733043.1	RAB	9..170	CDD:197555	74/165 (45%)
rab-35	NP_499454.1	Rab35	5..208	CDD:133310	85/213 (40%)
rab-35	NP_499454.1	RAB	11..171	CDD:197555	73/161 (45%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1149105at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.920