Protein Alignment RabX4 and RAB31

DIOPT Version :10

• Sequence 1: NP_733043.1
• Gene: RabX4 / 42960
• FlyBaseID: FBgn0051118
• Length: 213
• Species: Drosophila melanogaster
• Sequence 2: NP_006859.2
• Gene: RAB31 / 11031
• HGNCID: 9771
• Length: 195
• Species: Homo sapiens
• Alignment Length: 203
• Identity: 69/203 - (33%)
• Similarity: 106/203 - (52%)
• Gaps: 17/203 - (8%)

  Fly    10 KVLVLGDSNVGKTCIVHRYCDEKYYDTYIS-TIGIDFKQKLINLDGVPIKLQIWDTAGQERFRTL 73
            ||.:|||:.|||:.||.|:..: ::|..|| |||..|..|.:.......|..||||||||||.:|
Human     8 KVCLLGDTGVGKSSIVCRFVQD-HFDHNISPTIGASFMTKTVPCGNELHKFLIWDTAGQERFHSL 71

  Fly    74 TTAYYRGAMGILLMYDVTNLESYNNLSYWLRNIQENASPDVVKVLAGNKCECSATQRMVDKERGE 138
            ...||||:...:::||:|..:|:..|..|::.::|:...::|..:|||||:.|.. |.|..:..:
Human    72 APMYYRGSAAAVIVYDITKQDSFYTLKKWVKELKEHGPENIVMAIAGNKCDLSDI-REVPLKDAK 135

  Fly   139 KIAENFDMPFFEVSCKSNINIEDAFLSLARKIREQRERRGDNFDNDESKDKKSPGSNGLGTFSLG 203
            :.||:......|.|.|:.||||:.|..::|:|              ...|....|:||.......
Human   136 EYAESIGAIVVETSAKNAINIEELFQGISRQI--------------PPLDPHENGNNGTIKVEKP 186

  Fly   204 SLSGENRC 211
            ::....||
Human   187 TMQASRRC 194

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RabX4	NP_733043.1	RAB	9..170	CDD:197555	62/160 (39%)
RAB31	NP_006859.2	Rab5_related	6..168	CDD:206653	63/175 (36%)
		Switch 1. /evidence=ECO:0000250|UniProtKB:P20339	30..42		6/11 (55%)
		Switch 2. /evidence=ECO:0000250|UniProtKB:P20339	63..79		10/15 (67%)