DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment RabX4 and RAB40B

DIOPT Version :9

Sequence 1:	NP_733043.1	Gene:	RabX4 / 42960	FlyBaseID:	FBgn0051118	Length:	213	Species:	Drosophila melanogaster
Sequence 2:	NP_006813.1	Gene:	RAB40B / 10966	HGNCID:	18284	Length:	278	Species:	Homo sapiens

Alignment Length:	167	Identity:	71/167 - (42%)
Similarity:	100/167 - (59%)	Gaps:	4/167 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 ALDFVATYKVLVLGDSNVGKTCIVHRYCDEKYYDTYISTIGIDFKQKLINLDGVPIKLQIWDTAG 66
            |.||:  .|.|::|||:|||..|:....|......|....|||:|...|.|||..:|||:|||:|
Human    10 AYDFL--LKFLLVGDSDVGKGEILASLQDGAAESPYGHPAGIDYKTTTILLDGRRVKLQLWDTSG 72

  Fly    67 QERFRTLTTAYYRGAMGILLMYDVTNLESYNNLSYWLRNIQENASPDVVKVLAGNKCECSATQRM 131
            |.||.|:..:|.|||.|::|:||:.|..|::.:..|::.|.|:| |.|.|:|.||:... |.:|.
Human    73 QGRFCTIFRSYSRGAQGVILVYDIANRWSFDGIDRWIKEIDEHA-PGVPKILVGNRLHL-AFKRQ 135

  Fly   132 VDKERGEKIAENFDMPFFEVSCKSNINIEDAFLSLAR 168
            |..|:.:..||...:.|||||...|.||.::|..|||
Human   136 VPTEQAQAYAERLGVTFFEVSPLCNFNITESFTELAR 172

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
RabX4	NP_733043.1	RAB	9..170	CDD:197555	68/160 (43%)
RAB40B	NP_006813.1	Rab40	9..278	CDD:133321	71/167 (43%)
		SOCS_Rab40	187..229	CDD:239711
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	242..278
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0078
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810