Protein Alignment niki and HERC1

DIOPT Version :9

• Sequence 1: NP_651293.1
• Gene: niki / 42959
• FlyBaseID: FBgn0045980
• Length: 841
• Species: Drosophila melanogaster
• Sequence 2: XP_016878188.1
• Gene: HERC1 / 8925
• HGNCID: 4867
• Length: 4909
• Species: Homo sapiens
• Alignment Length: 488
• Identity: 118/488 - (24%)
• Similarity: 194/488 - (39%)
• Gaps: 82/488 - (16%)

  Fly   260 HAQTVLGTPYYFSPEMCEGKEYDNKSDIWA-LGCILGEMCCLKKTFAASNLSELVTKIMAGNYTP 323
            |.|..|..|..::|            :.|| |.|.   ...:|...|.:|.::........:..|
Human  3956 HHQNCLPDPASWNP------------NEWAWLECF---STTIKAAEALTNGAQFPESFTVPDLEP 4005

  Fly   324 VPSGYTSGLRSLMSNLLQVEAPRRPTASEVLVYWI---PLIFRSLGKNKGYSYEDDVGGPGSDQL 385
            ||.   ..|..||.|...:..     ..|.::.|.   |..:...||...|.:    |.....||
Human  4006 VPE---DELVFLMDNSKWING-----MDEQIMSWATSRPEDWHLGGKCDVYLW----GAGRHGQL 4058

  Fly   386 TAPVPAAAYSNVSMELELPTAQTETKQLMIADTAAPHEILEKRSVLYQLKAFGTCFS-------- 442
                 |.|..||.    :|.|.....|        ..:::..::..:.::|.||..:
Human  4059 -----AEAGRNVM----VPAAAPSFSQ--------AQQVICGQNCTFVIQANGTVLACGEGSYGR 4106

  Fly   443 --------------MAPIQLPPKAVIVDVAMSDSHFVVVNEDGSAYAWGEGTHGQLGLTALEAWK 493
                          ::.:|......:|....||.|.:.:.|.|..::||:|.:|:||....:..:
Human  4107 LGQGNSDDLHVLTVISALQGFVVTQLVTSCGSDGHSMALTESGEVFSWGDGDYGKLGHGNSDRQR 4171

  Fly   494 HYPSRMESVRNYHVVSACAGDGFTILVTQAGSLLSCGSNAHLALGQDEQRNYHSPKLIARLADVR 558
            . |.::|:::...||....|...:.:||..|.|.:.|:..:..||.....|...|:.:..|...:
Human  4172 R-PRQIEALQGEEVVQMSCGFKHSAVVTSDGKLFTFGNGDYGRLGLGNTSNKKLPERVTALEGYQ 4235

  Fly   559 VEQVAAGLQHVLALSREGA-VYVWGTSTCGALGLGNYQQQQKFPQKI-LLSHVKTKPSKIYCGPD 621
            :.|||.||.|.||:|.:|: |:.:|....|.||||| ...:..|||| :|..:..|  |:.||..
Human  4236 IGQVACGLNHTLAVSADGSMVWAFGDGDYGKLGLGN-STAKSSPQKIDVLCGIGIK--KVACGTQ 4297

  Fly   622 TSAVLFANGELHVCGSNDYNKLGFQRSAKITAFKKVQLPHK----VTQACFSSTHSVFLVEGGYV 682
            .|..|..:|.::..|.:  ..:|..........:..|:|..    :......:.|::.|...|.|
Human  4298 FSVALTKDGHVYTFGQD--RLIGLPEGRARNHNRPQQIPVLAGVIIEDVAVGAEHTLALASNGDV 4360

  Fly   683 YTMGRNAEGQRGIRHCNSVDHPTLVDSVKSRYI 715
            |..|.|:|||.|:.|.|.|..||||..::.:.:
Human  4361 YAWGSNSEGQLGLGHTNHVREPTLVTGLQGKNV 4393

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
niki	NP_651293.1	STKc_Nek	104..359	CDD:270855	21/102 (21%)
		S_TKc	105..354	CDD:214567	20/94 (21%)
		ATS1	445..747	CDD:227511	80/277 (29%)
HERC1	XP_016878188.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1062377at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.920