DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment niki and NEK1

DIOPT Version :9

Sequence 1:	NP_651293.1	Gene:	niki / 42959	FlyBaseID:	FBgn0045980	Length:	841	Species:	Drosophila melanogaster
Sequence 2:	NP_001185224.1	Gene:	NEK1 / 841893	AraportID:	AT1G54510	Length:	612	Species:	Arabidopsis thaliana

Alignment Length:	254	Identity:	93/254 - (36%)
Similarity:	151/254 - (59%)	Gaps:	2/254 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly   102 LANYEKVRVVGQGSFGIAILYRRKSDGHQIVFKQINLSELSPPGRDLAMNEVDVFSKLHHPNIVS 166
            :..||.:..:|:||||.|:|.|.|.:..:.|.|:|.|:..:...|..|..|:::.||:.||.||.
plant     1 MEQYEFLEQIGKGSFGSALLVRHKHEKKKYVLKKIRLARQTQRTRRSAHQEMELISKMRHPFIVE 65

  Fly   167 YLGSFI-KDNTLLIEMEYADGGTLAQIIAERQGKLHFPERYIIAVFEQISSAINYMHSENILHRD 230
            |..|:: |...:.|.:.|.:||.:||.|.:..| :||.|..:.....|:...:.|:||.:|||||
plant    66 YKDSWVEKACYVCIVIGYCEGGDMAQAIKKSNG-VHFQEEKLCKWLVQLLMGLEYLHSNHILHRD 129

  Fly   231 LKTANVFLNRRGIVKIGDFGISKIMNTKIHAQTVLGTPYYFSPEMCEGKEYDNKSDIWALGCILG 295
            :|.:|:||.:...:::||||::||:.:.....:|:|||.|..||:.....|.:|||||:|||.:.
plant   130 VKCSNIFLTKEQDIRLGDFGLAKILTSDDLTSSVVGTPSYMCPELLADIPYGSKSDIWSLGCCIY 194

  Fly   296 EMCCLKKTFAASNLSELVTKIMAGNYTPVPSGYTSGLRSLMSNLLQVEAPRRPTASEVL 354
            ||..||..|.|.::..|:.||.....:|:|:.|:...|.|:.::|:.....||:||::|
plant   195 EMAYLKPAFKAFDMQALINKINKTIVSPLPAKYSGPFRGLVKSMLRKNPEVRPSASDLL 253

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
niki	NP_651293.1	STKc_Nek	104..359	CDD:270855	93/252 (37%)
		S_TKc	105..354	CDD:214567	92/249 (37%)
		ATS1	445..747	CDD:227511
NEK1	NP_001185224.1	STKc_Nek	3..258	CDD:270855	93/252 (37%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	177	1.000	Domainoid score	I1076
eggNOG	1	0.900	-	-		E1_KOG0589
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000168
OrthoInspector	1	1.000	-	-		mtm947
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X891
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.810