DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment niki and AT5G42140

DIOPT Version :9

Sequence 1:	NP_651293.1	Gene:	niki / 42959	FlyBaseID:	FBgn0045980	Length:	841	Species:	Drosophila melanogaster
Sequence 2:	NP_001318728.1	Gene:	AT5G42140 / 834219	AraportID:	AT5G42140	Length:	1078	Species:	Arabidopsis thaliana

Alignment Length:	746	Identity:	159/746 - (21%)
Similarity:	243/746 - (32%)	Gaps:	247/746 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly   122 YRRKSDGHQIVF------KQINLSELSP--PGRDLAMNEVDVFSKLHHPNIVSYLG-SFIKDN-- 175
            :|..:|...:::      |::.|:.:|.  ||:..|     ||.:...|: ..||. |.|..|
plant    41 FRLSNDETSLIWISNGGEKRLKLATVSKIVPGQRTA-----VFQRYLRPD-KDYLSFSLIYSNRK 99

  Fly   176 -TL------LIEME---------------------YADGGTLAQIIAERQGKLHFPERYIIAVFE 212
             ||      .:|.|                     ::|||  ..|...|...|..|....:....
plant   100 RTLDLICKDKVEAEVWIAGLKALISGQAGRSKIDGWSDGG--LSIADSRDLTLSSPTNSSVCASR 162

  Fly   213 QISSAINYMHSENILHRDLKTANVFLNRRGIVKIGD--------------FGISKIMNTKIHAQT 263
            ..:.|.:..:|.| ..|..:|.|...:.|..|....              ..:|.:.::..|..
plant   163 DFNIADSPYNSTN-FPRTSRTENSVSSERSHVASDSPNMLVRGTGSDAFRVSVSSVQSSSSHGS- 225

  Fly   264 VLGTPYYFSPEMCE--GKEYDNKSDIWALGCILGEMCCLKKTFAASNLSELVTKIMAGNYTPVPS 326
                    :|:.|:  |..|     ||      ||:.|           |.|||..|
plant   226 --------APDDCDALGDVY-----IW------GEVLC-----------ENVTKFGA-------- 252

  Fly   327 GYTSGLRSLMSNLLQVEAPRRPTASEVLVYWIPLIFRSLGKNKGYSYEDDVGGPGSDQLTAPVPA 391
                                                   .||.||.      |..||.|   :|.
plant   253 ---------------------------------------DKNIGYL------GSRSDVL---IPK 269

  Fly   392 AAYSNVSMELE----------LPTAQTET-----------KQLMIADTAAPHEILEKRSVLYQLK 435
            ...|||.:::.          |.:.|.|.           ...|..|...| :::|
plant   270 PLESNVVLDVHHIACGVKHAALVSRQGEVFTWGEASGGRLGHGMGKDVTGP-QLIE--------- 324

  Fly   436 AFGTCFSMAPIQLPPKAVIVD-VAMSDSHFVVVNEDGSAYAWGEGTH--GQLGL-TALEAWKHYP 496
                  |:|       |..:| ||..:.|...|...|..|.||:|||  |.||. |.:..|  .|
plant   325 ------SLA-------ATSIDFVACGEFHTCAVTMTGEIYTWGDGTHNAGLLGHGTDVSHW--IP 374

  Fly   497 SRMES-VRNYHVVSACAGDGFTILVTQAGSLLSCGSNAHLALGQDEQRNYHSPKLIARLADVRVE 560
            .|:.. :....:.|...|...|.|:|..|.|.:.|......||..::.....|:.:..|:.:|..
plant   375 KRISGPLEGLQIASVSCGPWHTALITSTGQLFTFGDGTFGVLGHGDKETVFYPREVESLSGLRTI 439

  Fly   561 QVAAGLQHVLALSR-----------EGAVYVWGTSTCGALGLGNYQQQQKFPQKI--LLSHVKTK 612
            .||.|:.|..|:..           .|.::.||......||.|:.:.:.| |..:  |:.|..
plant   440 AVACGVWHAAAIVEVIVTHSSSSVSSGKLFTWGDGDKSRLGHGDKEPRLK-PTCVSALIDHTF-- 501

  Fly   613 PSKIYCGPDTSAVLFANGELHVCGSNDYNKLGFQRS-AKITAFKKVQLPHKVTQACF-----SST 671
             .::.||...:..|..:|:::..||..|.:||...: .|:...    :..|:|:.|.     .:.
plant   502 -HRVACGHSLTVGLTTSGKVYTMGSTVYGQLGNPNADGKLPCL----VEDKLTKDCVEEIACGAY 561

  Fly   672 HSVFLVEGGYVYTMGRNAEGQRGIRHCNSVDHPTLVDSVKSRYIVKANCSDQCTIVASEDNIITV 736
            |...|.....|:|.|:.|.|:.|.........|||||::|.|::....|....|...    .:..
plant   562 HVAVLTSRNEVFTWGKGANGRLGHGDVEDRKAPTLVDALKERHVKNIACGSNFTAAI----CLHK 622

  Fly   737 W--GTRNG-----LPGIGST-------NCGL 753
            |  ||...     ....|.|       ||||
plant   623 WVSGTEQSQCSACRQAFGFTRKRHNCYNCGL 653

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
niki	NP_651293.1	STKc_Nek	104..359	CDD:270855	51/291 (18%)
		S_TKc	105..354	CDD:214567	51/286 (18%)
		ATS1	445..747	CDD:227511	81/332 (24%)
AT5G42140	NP_001318728.1	PH_PLC_plant-like	12..124	CDD:270171	20/88 (23%)
		ATS1	<282..614	CDD:227511	86/364 (24%)
		FYVE	621..689	CDD:214499	9/33 (27%)
		BRX_N	869..904	CDD:372684
		BRX	1003..1057	CDD:369842
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1062377at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920