DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment niki and NEK3

DIOPT Version :9

Sequence 1:	NP_651293.1	Gene:	niki / 42959	FlyBaseID:	FBgn0045980	Length:	841	Species:	Drosophila melanogaster
Sequence 2:	NP_001330383.1	Gene:	NEK3 / 832912	AraportID:	AT5G28290	Length:	568	Species:	Arabidopsis thaliana

Alignment Length:	254	Identity:	91/254 - (35%)
Similarity:	152/254 - (59%)	Gaps:	2/254 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly   102 LANYEKVRVVGQGSFGIAILYRRKSDGHQIVFKQINLSELSPPGRDLAMNEVDVFSKLHHPNIVS 166
            :.:||.:..:|:||||.|:|.|.|.:....|.|:|.|:..:...|..|..|:::.||:.:|.||.
plant     1 MEHYEVLEQIGKGSFGSALLVRHKHEKKLYVLKKIRLARQTGRTRRSAHQEMELISKIRNPFIVE 65

  Fly   167 YLGSFI-KDNTLLIEMEYADGGTLAQIIAERQGKLHFPERYIIAVFEQISSAINYMHSENILHRD 230
            |..|:: |...:.|.:.|..||.:|:.|.:..| :.|.|..:.....|:..|:.|:|:.:|||||
plant    66 YKDSWVEKGCYVCIVIGYCKGGDMAEAIKKANG-VEFSEEKLCKWLVQLLMALEYLHASHILHRD 129

  Fly   231 LKTANVFLNRRGIVKIGDFGISKIMNTKIHAQTVLGTPYYFSPEMCEGKEYDNKSDIWALGCILG 295
            :|.:|:||.:...:::||||::||:.:...|.:|:|||.|..||:.....|.:|||||:|||.:.
plant   130 VKCSNIFLTKDQDIRLGDFGLAKILTSDDLASSVVGTPSYMCPELLADIPYGSKSDIWSLGCCMY 194

  Fly   296 EMCCLKKTFAASNLSELVTKIMAGNYTPVPSGYTSGLRSLMSNLLQVEAPRRPTASEVL 354
            ||..||..|.|.::..|:.:|......|:|:.|::..|||:.::|:.....||:||::|
plant   195 EMTALKPAFKAFDMQGLINRINRSIVAPLPAQYSTAFRSLVKSMLRKNPELRPSASDLL 253

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
niki	NP_651293.1	STKc_Nek	104..359	CDD:270855	91/252 (36%)
		S_TKc	105..354	CDD:214567	90/249 (36%)
		ATS1	445..747	CDD:227511
NEK3	NP_001330383.1	STKc_Nek	3..258	CDD:270855	91/252 (36%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	177	1.000	Domainoid score	I1076
eggNOG	1	0.900	-	-		E1_KOG0589
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000168
OrthoInspector	1	1.000	-	-		mtm947
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X891
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.810