DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment niki and AT5G19420

DIOPT Version :9

Sequence 1:	NP_651293.1	Gene:	niki / 42959	FlyBaseID:	FBgn0045980	Length:	841	Species:	Drosophila melanogaster
Sequence 2:	NP_001190338.1	Gene:	AT5G19420 / 832062	AraportID:	AT5G19420	Length:	1139	Species:	Arabidopsis thaliana

Alignment Length:	731	Identity:	161/731 - (22%)
Similarity:	241/731 - (32%)	Gaps:	250/731 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly   229 RDLKTANVFLNRRGIVKIGDFGISK-----IMNTK--IHAQTVLGTPYYF-------SPEMCEGK 279
            ||::...:.|       ...||:||     |:..|  :||.|.|....|.       .|:.|..:
plant    27 RDIEQLKIEL-------YSTFGVSKLDSSYILENKNALHAITALKKGAYLLKYGRRGKPKFCPFR 84

  Fly   280 EYDNKSD-IWALGCILGEMCCLKKTFAASNLSELVTKIMAGNYTPVPSGYT-------------- 329
            ..:::|. ||..|          |......||. |::|::|..||:...|.
plant    85 LSNDESVLIWFSG----------KEEKHLKLSH-VSRIISGQRTPIFQRYPRPEKEYQSFSLIYD 138

  Fly   330 ------------------SGLRSLMSNLLQ----VEAPRRPTASEVLVYWIPLIFRSLGKNKGYS 372
                              |||::|:|...|    .|:....|.||.              |...:
plant   139 ERSLDLICKDKDEAEVWFSGLKALISRCHQRKWRTESRSDGTPSEA--------------NSPRT 189

  Fly   373 YEDDVGGPGSDQLTAPVPAAAYSNVSMELELPTAQTETKQLMIADTAAPHEILEKRSVLYQLKAF 437
            |         .:.::|:.:...||.|.:.|      .:..|.:   .:|:|...|..|   .|||
plant   190 Y---------TRRSSPLHSPFSSNESFQKE------GSNHLRL---HSPYESPPKNGV---DKAF 233

  Fly   438 GTCFSMAPIQLPPKA-----------------------------------VIVDVAMSDSHFVVV 467
            .   .|:...:|||.                                   |.:..|:|.|.....
plant   234 S---DMSLYAVPPKGFFPPGSATMSVHSLSSGGSDTLHGHMKGMGMDAFRVSLSSAISSSSHGSG 295

  Fly   468 NED----GSAYAWGEGTHGQLGLTALEAWKH-------------YPSRMESVRNYHVVSACAGDG 515
            ::|    |..:.||||    :|...|....|             .|..:||.....|.:...|..
plant   296 HDDGDTLGDVFMWGEG----IGEGVLGGGNHRVGSSLEIKMDSLLPKALESTIVLDVQNIACGGQ 356

  Fly   516 FTILVTQAGSLLSCGSNAHLALGQDEQRNYHSPKLIARLADVRVEQVAAGLQHVLALSREGAVYV 580
            ..:|||:.|...|.|..:...||.....|...||||..|....:|.||.|..|..|::..|.:|.
plant   357 HAVLVTKQGESFSWGEESEGRLGHGVDSNVQHPKLIDALNTTNIELVACGEYHSCAVTLSGDLYT 421

  Fly   581 WGTSTCGALGLGNYQQQQKFPQKI--LLS--HVKTKPSKIYCGPDTSAVLFANGELHVCGSNDYN 641
            ||....|.||.|| :.....|:::  |:.  ||    |.|.|||..:||:.:.|:|...|...:.
plant   422 WGKGDFGILGHGN-EVSHWVPKRVNFLMEGIHV----SSIACGPYHTAVVTSAGQLFTFGDGTFG 481

  Fly   642 KLGF----------------------------------------QRSAKITAFK--------KVQ 658
            .||.                                        ..|:..::.|        |.:
plant   482 VLGHGDRKSVFIPREVDSLKGLRTVRAACGVWHTAAVVEVMVGSSSSSNCSSGKLFTWGDGDKSR 546

  Fly   659 LPH-----KVTQACFSST-----------HS--VFLVEGGYVYTMGRNAEGQRGIRHCNSVDHPT 705
            |.|     |:...|.::.           ||  |.|...|:|||||....||.|..|.:. ..||
plant   547 LGHGDKEPKLVPTCVAALVEPNFCQVACGHSLTVALTTSGHVYTMGSPVYGQLGNPHADG-KVPT 610

  Fly   706 LVD-SVKSRYIVKANCSDQCTIVASEDNIITVWGT-RNGLPGIGSTNCGLGLQICTPNMELELGN 768
            .|| .:...::.:..|......|.:....:..||. .||..|.|..:     ...:|.:...|.:
plant   611 RVDGKLHKSFVEEIACGAYHVAVLTSRTEVYTWGKGSNGRLGHGDAD-----DRNSPTLVESLKD 670

  Fly   769 ----NTAAFTNFLASV 780
                :.|..:||.|:|
plant   671 KQVKSIACGSNFTAAV 686

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
niki	NP_651293.1	STKc_Nek	104..359	CDD:270855	39/180 (22%)
		S_TKc	105..354	CDD:214567	39/175 (22%)
		ATS1	445..747	CDD:227511	98/425 (23%)
AT5G19420	NP_001190338.1	PH_PLC_plant-like	57..164	CDD:270171	24/117 (21%)
		RCC1_2	348..377	CDD:290274	8/28 (29%)
		RCC1	365..413	CDD:278826	16/47 (34%)
		RCC1	416..466	CDD:278826	19/54 (35%)
		RCC1	470..518	CDD:278826	5/47 (11%)
		RCC1	534..582	CDD:278826	9/47 (19%)
		RCC1	585..634	CDD:278826	15/49 (31%)
		RCC1	639..686	CDD:278826	12/51 (24%)
		FYVE	690..757	CDD:279674
		Tup_N	906..956	CDD:285748
		BRX_N	949..984	CDD:290432
		BRX_assoc	990..1057	CDD:293233
		BRX	1064..1118	CDD:285568
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1062377at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920