DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment niki and NEK4

DIOPT Version :9

Sequence 1:	NP_651293.1	Gene:	niki / 42959	FlyBaseID:	FBgn0045980	Length:	841	Species:	Drosophila melanogaster
Sequence 2:	NP_001326588.1	Gene:	NEK4 / 825503	AraportID:	AT3G63280	Length:	609	Species:	Arabidopsis thaliana

Alignment Length:	385	Identity:	116/385 - (30%)
Similarity:	187/385 - (48%)	Gaps:	60/385 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   101 ELANYEKVRVVGQGSFGIAILYRRKSDGHQIVFKQINLSELSPPGRDLAMNEVDVFSKLHHPNIV 165
            ::..||.:..:|:||||.|:|.|.|.:..:.|.|:|.|:..|...|..|..|:::.|.:.:|.:|
plant    54 QMERYEVLEQIGKGSFGSALLVRHKQERKKYVLKKIRLARQSDRARRSAHQEMELISTVRNPFVV 118

  Fly   166 SYLGSFI-KDNTLLIEMEYADGGTLAQIIAERQGKLHFPERYIIAVFEQISSAINYMHSENILHR 229
            .|..|:: |...:.|.:.|..||.:...|....| :||||..:.....|:..|::|:||.:||||
plant   119 EYKDSWVEKGCYVCIVIGYCQGGDMTDTIKRACG-VHFPEEKLCQWLVQLLMALDYLHSNHILHR 182

  Fly   230 DLKTANVFLNRRGIVKIGDFGISKIMNTKIHAQTVLGTPYYFSPEMCEGKEYDNKSDIWALGCIL 294
            |:|.:|:||.:...:::||||::||:.:.....:|:|||.|..||:.....|.:|||||:|||.:
plant   183 DVKCSNIFLTKEQDIRLGDFGLAKILTSDDLTSSVVGTPSYMCPELLADIPYGSKSDIWSLGCCM 247

  Fly   295 GEMCCLKKTFAASNLSELVTKIMAGNYTPVPSGYTSGLRSLMSNLLQVEAPRRPTASEVL----- 354
            .||...|..|.||::..|:|||......|:|:.|:...|.|:.::|:.....||:|:|:|
plant   248 YEMAAHKPPFKASDVQTLITKIHKLIMDPIPAMYSGSFRGLIKSMLRKNPELRPSANELLNHPHL 312

  Fly   355 ------VYW---------IPLIF----RSLGKNKGYSYEDD-----------VGGPGSDQLTAPV 389
                  ||.         .||.|    .:|.:.:..|:.:|           .|...|....:|.
plant   313 QPYISMVYMKLESPRRSTFPLQFSERDATLKERRRSSFSNDRRLNPSVSDTEAGSVSSSGKASPT 377

  Fly   390 PAAAYSNVS-------MELELPTAQTETKQL-------MIADTAA---------PHEILE 426
            |......||       .|..:|..|.|.|:.       .:|.|:|         .||:::
plant   378 PMFNGRKVSEVTVGVVREEIVPQRQEEAKKQSGAARTPRVAGTSAKASTQRTVFKHELMK 437

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
niki	NP_651293.1	STKc_Nek	104..359	CDD:270855	94/275 (34%)
		S_TKc	105..354	CDD:214567	91/249 (37%)
		ATS1	445..747	CDD:227511
NEK4	NP_001326588.1	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	177	1.000	Domainoid score	I1076
eggNOG	1	0.900	-	-		E1_KOG0589
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000168
OrthoInspector	1	1.000	-	-		mtm947
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X891
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.810