Protein Alignment niki and NEK11

DIOPT Version :9

• Sequence 1: NP_651293.1
• Gene: niki / 42959
• FlyBaseID: FBgn0045980
• Length: 841
• Species: Drosophila melanogaster
• Sequence 2: NP_001308150.1
• Gene: NEK11 / 79858
• HGNCID: 18593
• Length: 687
• Species: Homo sapiens
• Alignment Length: 401
• Identity: 123/401 - (30%)
• Similarity: 182/401 - (45%)
• Gaps: 91/401 - (22%)

  Fly   102 LANYEKVRV---------VGQGSFGIAILY--RRKSDGHQI-VFKQINLSELSPPGRDLAMNEVD 154
            ::.|.|..:         :|.||||...|.  ::...|.:: |.|:|::.||:|.....|..|..
Human    17 ISTYPKTLIARRYVLQQKLGSGSFGTVYLVSDKKAKRGEELKVLKEISVGELNPNETVQANLEAQ 81

  Fly   155 VFSKLHHPNIVSYLGSFIKDNTLLIEMEYAD---------------------------------- 185
            :.|||.||.||.:..||::.:...|..||.:
Human    82 LLSKLDHPAIVKFHASFVEQDNFCIITEYCEDLSKENCKPLLNEIKEDTNKWKNIPCSWVGRINI 146

  Fly   186 --------GGTLAQIIAE--RQGKLHFPERYIIAVFEQISSAINYMHSENILHRDLKTANVFLNR 240
                    |..|...|.|  :.||: |||..||..|.|:...::|||...|||||||:.|||| :
Human   147 VKMAILPKGRDLDDKIQEYKQAGKI-FPENQIIEWFIQLLLGVDYMHERRILHRDLKSKNVFL-K 209

  Fly   241 RGIVKIGDFGISK-IMNTKIHAQTVLGTPYYFSPEMCEGKEYDNKSDIWALGCILGEMCCLKKTF 304
            ..::||||||:|: :|.:...|.|:.|||:|.|||..:.:.||.|||||:|.|||.||||:...|
Human   210 NNLLKIGDFGVSRLLMGSCDLATTLTGTPHYMSPEALKHQGYDTKSDIWSLACILYEMCCMNHAF 274

  Fly   305 AASNLSELVTKIMAGNYTPVPSGYTSGLRSLMSNLLQVEAPRRPTASEVLVYWIPLIFRSLGKNK 369
            |.||...:|.||:.|:...:|..|...|.::|.::|......||:|.|:|.  ||.:
Human   275 AGSNFLSIVLKIVEGDTPSLPERYPKELNAIMESMLNKNPSLRPSAIEILK--IPYL-------- 329

  Fly   370 GYSYEDDVGGPGSDQLTAPVPAAAYSNVSMELELPTAQTETKQLMIADTAAPHEILEKRSVLYQL 434
                        .:||...:  ..||.:::|.:....|.|...::.|        ::||..|..|
Human   330 ------------DEQLQNLM--CRYSEMTLEDKNLDCQKEAAHIINA--------MQKRIHLQTL 372

  Fly   435 KAFGTCFSMAP 445
            :|......|.|
Human   373 RALSEVQKMTP 383

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
niki	NP_651293.1	STKc_Nek	104..359	CDD:270855	106/311 (34%)
		S_TKc	105..354	CDD:214567	105/305 (34%)
		ATS1	445..747	CDD:227511	1/1 (100%)
NEK11	NP_001308150.1	STKc_Nek11	28..329	CDD:270861	106/304 (35%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0589
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D132059at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.820