Protein Alignment niki and nek4

DIOPT Version :10

• Sequence 1: NP_651293.1
• Gene: niki / 42959
• FlyBaseID: FBgn0045980
• Length: 841
• Species: Drosophila melanogaster
• Sequence 2: NP_001072768.1
• Gene: nek4 / 780225
• XenbaseID: XB-GENE-5914376
• Length: 791
• Species: Xenopus tropicalis
• Alignment Length: 525
• Identity: 154/525 - (29%)
• Similarity: 230/525 - (43%)
• Gaps: 101/525 - (19%)

  Fly   102 LANYEKVRVVGQGSFGIAILYRRKSDGHQIVFKQINLSELSPPGRDLAMNEVDVFSKLHHPNIVS 166
            |..|..:|.||:||:|...|.|.::.|.|.|.|::||...|...|..|..|..:.|.|.|||||:
 Frog     7 LGEYVLIRPVGKGSYGEVSLVRHRTLGKQFVIKKLNLQSASRRERKAAEQEARLLSHLKHPNIVA 71

  Fly   167 YLGSFI-KDNTLLIEMEYADGGTLAQIIAERQGKLHFPERYIIAVFEQISSAINYMHSENILHRD 230
            |..|:. :|..|.|.|.:.:||.|...:.|::||| ..|..::..|.||:.|:.|:|.|:|:|||
 Frog    72 YRESWEGEDGMLYIAMGFCEGGDLYHKLKEQKGKL-LLESQVMDWFIQIAMALQYLHEEHIMHRD 135

  Fly   231 LKTANVFLNRRGIVKIGDFGISKIMNTKIH-AQTVLGTPYYFSPEMCEGKEYDNKSDIWALGCIL 294
            |||.||||.|..|:|:||.||::::.::.. |.|::|||||.|||:...|.|:.|||:|||||.:
 Frog   136 LKTQNVFLTRSNIIKVGDLGIARVLESQYDMASTLIGTPYYMSPELFSNKPYNYKSDVWALGCCV 200

  Fly   295 GEMCCLKKTFAASNLSELVTKIMAGNYTPVPSGYTSGLRSLMSNLLQVEAPRRPTASEVL----- 354
            .|:..|:..|.|.:::.||.:|:.|...|:|..|:..|..|::.:|..:..:||:..::|
 Frog   201 YEIATLRHAFNAKDMNSLVYRIIEGKLPPMPKDYSKELGDLIATMLNRQPEKRPSVKQILHKPFI 265

  Fly   355 VYWIPLIFRSL--------GKNKGYSYEDDVGGPGSDQLTAPVPAAAYSNVSMELELPTAQTETK 411
            .:.|.|..::.        .|....|..|....|..:....|.||..          |..:...|
 Frog   266 RHHISLFLQATKLKHCKHKRKVSASSLSDIPASPQHEDPALPKPACD----------PPRKVPPK 320

  Fly   412 QLMIADTAAPHEILEKRSVLYQLKAFGTCFSMAPIQLPPKA---------VIVDVAMSDSHFVVV 467
            :|              ||:...:.| |:..|.:.|..|..|         .:..::..|......
 Frog   321 KL--------------RSLAKNVPA-GSAPSSSDIGAPEPANNGLSHTGVSLATLSNVDIGIAAA 370

  Fly   468 NEDGSA----YAWGEGTHG-----------QLGLTALEAWKH---------------YPSRMESV 502
            ..|.||    ...|...:|           |||....|...|               :||.||.
 Frog   371 EHDRSAPDHPIPAGNPANGHVTEQPERRRVQLGSHTAEGKAHLNSISRVEKSHSGALHPSNMEE- 434

  Fly   503 RNYHVVSACAGDGFTILVTQAGSLLSCGSNAHLALGQDEQRNYHSPKLIARLADVRVEQVAAGLQ 567
                       .|.|:.:.|.|:       .|.....||:.. .:.||:.....| :||.||...
 Frog   435 -----------QGDTMKLLQPGT-------QHGKSPTDEELE-STDKLLEPFVPV-MEQAAASHA 479

  Fly   568 HVLAL 572
            ...||
 Frog   480 EKAAL 484

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
niki	NP_651293.1	STKc_Nek	104..359	CDD:270855	102/261 (39%)
		ATS1	433..749	CDD:444065	37/179 (21%)
nek4	NP_001072768.1	STKc_Nek4	9..265	CDD:270862	102/256 (40%)