DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment niki and nek7

DIOPT Version :9

Sequence 1:	NP_651293.1	Gene:	niki / 42959	FlyBaseID:	FBgn0045980	Length:	841	Species:	Drosophila melanogaster
Sequence 2:	NP_001072574.1	Gene:	nek7 / 780029	XenbaseID:	XB-GENE-962512	Length:	302	Species:	Xenopus tropicalis

Alignment Length:	261	Identity:	98/261 - (37%)
Similarity:	157/261 - (60%)	Gaps:	12/261 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly   102 LANYEKVRVVGQGSFGIAILYRRKS--DGHQIVFKQINLSEL-SPPGRDLAMNEVDVFSKLHHPN 163
            |||::..:::|:|.|  :.:||...  ||..:..|::.:.:| ....|...:.|:|:..:|:|||
Frog    31 LANFQIGKMIGRGQF--SEVYRATCLLDGVPVALKKVQIFDLMDAKARADCIKEIDLLKQLNHPN 93

  Fly   164 IVSYLGSFIKDNTLLIEMEYADGGTLAQIIA--ERQGKLHFPERYIIAVFEQISSAINYMHSENI 226
            ::.|..|||:||.|.|.:|.||.|.|:::|.  ::|.:| .||:.:...|.|:.||:.:|||..:
Frog    94 VIKYYASFIEDNELNIVLELADAGDLSRMIKHFKKQKRL-IPEKTVWKYFVQLCSALEHMHSRRV 157

  Fly   227 LHRDLKTANVFLNRRGIVKIGDFGISKIMNTK-IHAQTVLGTPYYFSPEMCEGKEYDNKSDIWAL 290
            :|||:|.||||:...|:||:||.|:.:..::| ..|.:::|||||.|||......|:.|||||:|
Frog   158 MHRDIKPANVFITATGVVKLGDLGLGRFFSSKTTAAHSLVGTPYYMSPERIHENGYNFKSDIWSL 222

  Fly   291 GCILGEMCCLKKTFAAS--NLSELVTKIMAGNYTPVPSG-YTSGLRSLMSNLLQVEAPRRPTASE 352
            ||:|.||..|:..|...  ||..|..||...:|.|:||. |:..||.|::..:..:..:||..:.
Frog   223 GCLLYEMAALQSPFYGDKMNLYSLCKKIEQCDYPPLPSDHYSEELRMLVNTCINPDPEKRPDVTY 287

  Fly   353 V 353
            |
Frog   288 V 288

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
niki	NP_651293.1	STKc_Nek	104..359	CDD:270855	96/259 (37%)
		S_TKc	105..354	CDD:214567	95/258 (37%)
		ATS1	445..747	CDD:227511
nek7	NP_001072574.1	STKc_Nek6_7	33..294	CDD:270863	96/259 (37%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000168
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000