DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment niki and hectd3

DIOPT Version :9

Sequence 1:	NP_651293.1	Gene:	niki / 42959	FlyBaseID:	FBgn0045980	Length:	841	Species:	Drosophila melanogaster
Sequence 2:	NP_001072497.1	Gene:	hectd3 / 779952	XenbaseID:	XB-GENE-5937967	Length:	845	Species:	Xenopus tropicalis

Alignment Length:	174	Identity:	41/174 - (23%)
Similarity:	62/174 - (35%)	Gaps:	34/174 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   508 VSACAGDGFTILVTQAGSLLSCGSNAHLALGQD--EQRN-YHSPKLIARLADVR------VEQVA 563
            ::.|..:|..:.:  .|..:.......|.|..|  :..| ...|:|.|...||.      |::..
Frog   337 ITQCLDEGIDVRI--RGLKIKSSKRRDLGLTADLFQPNNLVRYPRLEAIEPDVLYHRAVVVQRFV 399

  Fly   564 AGLQHVLALSREGAVYVWGTSTCGALGLGNYQQQQKFPQKILLSHVKTKPSKI-YC-------GP 620
            ..|.:||    ...|..|..|      :|.:.|.:...|.:|||  |.:.|.| .|       .|
Frog   400 KLLDNVL----NHMVPAWDHS------IGTFNQLKHIKQFLLLS--KCRSSLITQCLKDSETMKP 452

  Fly   621 DTSAVLFANGELHVCGSNDYNKLGFQRSAKITAFKKVQLPHKVT 664
            |....|:.|..:.|   ...:......|.|.|.|.:|....|:|
Frog   453 DFMPCLYINRRIAV---EHRDNPSLDPSYKKTVFSQVYEGLKLT 493

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
niki	NP_651293.1	STKc_Nek	104..359	CDD:270855
		S_TKc	105..354	CDD:214567
		ATS1	445..747	CDD:227511	41/174 (24%)
hectd3	NP_001072497.1	APC10-HECTD3	222..355	CDD:176487	3/19 (16%)
hectd3	NP_001072497.1	HECTc	512..837	CDD:421431
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1062377at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010