Protein Alignment niki and nek11

DIOPT Version :9

• Sequence 1: NP_651293.1
• Gene: niki / 42959
• FlyBaseID: FBgn0045980
• Length: 841
• Species: Drosophila melanogaster
• Sequence 2: NP_001072436.1
• Gene: nek11 / 779890
• XenbaseID: XB-GENE-955651
• Length: 601
• Species: Xenopus tropicalis
• Alignment Length: 648
• Identity: 180/648 - (27%)
• Similarity: 266/648 - (41%)
• Gaps: 139/648 - (21%)

  Fly    77 MPNRQESLLQLSVPRETGVGVAGPELA--------NYEKVRVVGQGSFG-IAILYRRKSDGHQ-- 130
            |||.||......         |||..|        .|...:.:|:|||| :.::..:|:...|
 Frog     1 MPNIQECERMCH---------AGPLSACTDTLIAKRYLLQQRLGKGSFGTVYLVIDKKAKDEQES 56

  Fly   131 -IVFKQINLSELSPPGRDLAMNEVDVFSKLHHPNIVSYLGSFIKDNTLLIEMEYADGGTLAQIIA 194
             .|.|:|.:.||:|.....|..|..:.|||.||.||.:..||:::.:..|..||.:|..|...:.
 Frog    57 LKVLKEIPVGELNPNETVQANVEAQLLSKLDHPAIVKFHASFLENESFCIITEYCEGRDLDFKVR 121

  Fly   195 E-RQGKLHFPERYIIAVFEQISSAINYMHSENILHRDLKTANVFLNRRGIVKIGDFGISK-IMNT 257
            | ::.:....|..::..|.|:...:||||...|||||||..|:|| :..::||||||:|: :|.:
 Frog   122 ECKKNEEKIAENQVVEWFIQLLLGVNYMHVRRILHRDLKAKNIFL-KNNLLKIGDFGVSRLLMGS 185

  Fly   258 KIHAQTVLGTPYYFSPEMCEGKEYDNKSDIWALGCILGEMCCLKKTFAASNLSELVTKIMAGNYT 322
            ...|.|..|||||.|||..:.:.||:|||||:|||||.|||||:..|...|...:|..|:.|...
 Frog   186 CDLATTFTGTPYYMSPEALKHQGYDSKSDIWSLGCILHEMCCLEHAFIGYNFLSVVISIVEGETP 250

  Fly   323 PVPSGYTSGLRSLMSNLLQVEAPRRPTASEVLVYWIPLIFRSLGKNKGYSYEDDVGG------PG 381
            .:|..|:|.|..:|:.:|..:...||:|.|:|  ..|.|...|.:.|...|..:|..      ..
 Frog   251 SLPDCYSSSLNLIMNRMLNKDPALRPSAGEIL--QDPFINEQLKQVKWEVYGAEVKDKTTICKKE 313

  Fly   382 SDQLTAPVPAAAYSNVSMELE-----LPTAQTETKQLMIADTAAPH--------------EILEK 427
            :||:...|....:.....||.     .|..:...::|..||..|..              .:.|.
 Frog   314 ADQIRNVVQRKFHLQTLRELSEVQKMTPRERMRLRKLNAADEKARRLKQLAEEKYQENHKRMQEL 378

  Fly   428 RSVLYQLKAFGTCFSMAPIQLPPKAVIVDVAMSD-SHFVVVNEDGSAYAW------GEGTHGQLG 485
            ||..:||.:..               ::.|...| |:.::.:|..||..:      .|....|..
 Frog   379 RSRNFQLHSID---------------VLHVQQDDTSNHLIQSEPMSARHYTPQSYEDESEDIQDR 428

  Fly   486 LTALEAWKHYPSRMESVRNYHVVSACAGDGFTILVTQAGSLLSCGSNAHLALGQDEQRNYHSPKL 550
            |.|.|     ||| |...:..|..|...|||.          ||...:...:  :|:..|.|...
 Frog   429 LCASE-----PSR-EIPEDPCVADAYYEDGFD----------SCSEESDECV--EEEDEYDSGSQ 475

  Fly   551 IARLADVRVEQVAAGLQHVLALS---------------------------------REGAVYVWG 582
            |....|..|:.:...|:.|||.|                                 ||.||...|
 Frog   476 ITYQQDSDVKAMVLHLEDVLASSCFDTDAATNMSPPIPLRSRAINDTMAQTKLKRMRESAVQSMG 540

  Fly   583 TSTCGALGLGNYQ-----QQQKFPQKIL---LSHVKTKPSKIYCGPDTSAVLFANGELHVCGS 637
            ..:...:    |.     :|.|..:|.:   |..:.:|||:.:.   ...:|:...||.|..|
 Frog   541 KKSFDKV----YSYLKSARQNKTSEKEVKKQLESMVSKPSECFI---VDQLLYFEEELAVISS 596

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
niki	NP_651293.1	STKc_Nek	104..359	CDD:270855	99/260 (38%)
		S_TKc	105..354	CDD:214567	98/254 (39%)
		ATS1	445..747	CDD:227511	51/241 (21%)
nek11	NP_001072436.1	STKc_Nek11	27..287	CDD:270861	100/262 (38%)
		S_TKc	28..287	CDD:214567	100/261 (38%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D132059at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920