DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment niki and sergef

DIOPT Version :9

Sequence 1:	NP_651293.1	Gene:	niki / 42959	FlyBaseID:	FBgn0045980	Length:	841	Species:	Drosophila melanogaster
Sequence 2:	NP_001072233.1	Gene:	sergef / 779680	XenbaseID:	XB-GENE-6455308	Length:	349	Species:	Xenopus tropicalis

Alignment Length:	358	Identity:	96/358 - (26%)
Similarity:	145/358 - (40%)	Gaps:	77/358 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   428 RSVLY--------QLKAFGTCFSMAP---IQLP-PKAVIVDVAMSDSHFVVVNEDGSAYAWGEGT 480
            |.:||        ||....|..:..|   |.|| .:.||..::....|...|.|.|..|..|:.:
Frog     8 RQLLYAWGANSYGQLGVGSTQDTPVPQLVIGLPNHETVIRSISAGGGHSAAVTESGRVYVCGQNS 72

  Fly   481 HGQLGL---TALEAWKHYPSRMESVRNYHVVSACAGDGFTILVTQAGSLLSCGSNAHLALGQDEQ 542
            .|||||   |.:..:...|..:    ...|.....|..||:::.:.|.|||||:|.:..||:...
Frog    73 EGQLGLDHTTDVTQFCLCPGAL----GLRVSKVSCGWDFTLILAETGELLSCGANTYSQLGRAGA 133

  Fly   543 RNYHSPKLIARLADVRVEQVAAGLQHVLALSREGAVYVWGTSTCGALGLGNYQQQQKFPQKILLS 607
            .....|:.:. :...:|..|||||:|||||:..|.::.||:      ||.::.::......|...
Frog   134 GRSCVPRPVG-IQKRKVIDVAAGLRHVLALTDNGQIFQWGS------GLASHARRFSPQNPIPPV 191

  Fly   608 HVKTKPSKI-----YCGPDTSA------VLFANGELHVCGSNDYNKLGFQRSAKITAFKKVQLPH 661
            :..|:|..:     .||...:|      .|...|:::..|||.:.:|       :.....:..||
Frog   192 YGATEPCPVPGMEGICGKVVTAGSYHCVALSDAGDMYAWGSNKHGQL-------LHPDPFLLHPH 249

  Fly   662 KVTQACF-----------SSTHSVFLVEGGYVYTMGR----------NAEGQ-------RGIRHC 698
            :| ||.|           ..||.|...:.|.|:|.||          :.||.       .|| ..
Frog   250 RV-QAHFFLGESIVAVTSGWTHLVAQTDTGKVFTWGRANYSQLGRPPSTEGTGLNETLLEGI-PA 312

  Fly   699 NSVDH--PTLVDSVKSR-YIVKANCSDQCTIVA 728
            |.|..  |:|..|.:.. ||..|..|.:|..:|
Frog   313 NQVPAWIPSLTGSSQMECYIPGAGMSTECAELA 345

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
niki	NP_651293.1	STKc_Nek	104..359	CDD:270855
		S_TKc	105..354	CDD:214567
		ATS1	445..747	CDD:227511	90/333 (27%)
sergef	NP_001072233.1	RCC1	11..>294	CDD:332518	80/301 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1062377at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010