DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment niki and Nek5

DIOPT Version :9

Sequence 1:	NP_651293.1	Gene:	niki / 42959	FlyBaseID:	FBgn0045980	Length:	841	Species:	Drosophila melanogaster
Sequence 2:	XP_008769592.1	Gene:	Nek5 / 685440	RGDID:	1593817	Length:	677	Species:	Rattus norvegicus

Alignment Length:	252	Identity:	100/252 - (39%)
Similarity:	163/252 - (64%)	Gaps:	7/252 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly   105 YEKVRVVGQGSFGIAILYRRKSDGHQIVFKQINLSELSPPGRDLAMNEVDVFSKLHHPNIVSYLG 169
            ::.::::|:|:||...|.:.||:....|.|:|:|::    .::.:.|||.:.:|:.|.|||::..
  Rat     4 FDLIKIIGEGTFGKVYLAKDKSESCHCVIKEISLTK----EKEASKNEVTLLAKMKHSNIVTFFS 64

  Fly   170 SFIKDNTLLIEMEYADGGTLAQIIAERQGKLHFPERYIIAVFEQISSAINYMHSENILHRDLKTA 234
            ||.:::.|.|.|||.|||.|.:.|..::|.| |.|..|:..|.|||..:.::|.:.:||||:|:.
  Rat    65 SFQENSRLFIVMEYCDGGDLMERIQRQRGVL-FSEDQILCWFVQISLGLKHIHDKKVLHRDIKSQ 128

  Fly   235 NVFLNRRGIV-KIGDFGISKIMNTKIH-AQTVLGTPYYFSPEMCEGKEYDNKSDIWALGCILGEM 297
            |:||::.|:| |:||||.::.:|..:. |||..|||||.|||:|:.:.|:||:|||:|||:|.|:
  Rat   129 NIFLSKNGMVAKLGDFGTARTLNNSMELAQTCAGTPYYLSPEICQNRPYNNKTDIWSLGCVLYEL 193

  Fly   298 CCLKKTFAASNLSELVTKIMAGNYTPVPSGYTSGLRSLMSNLLQVEAPRRPTASEVL 354
            |.||..|.:.||..||.||..|...|:...::..|:||:..|.:|....||:.:.:|
  Rat   194 CTLKHPFESDNLHHLVLKICQGRVAPISPHFSLDLQSLIPQLFRVSPQDRPSINSLL 250

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
niki	NP_651293.1	STKc_Nek	104..359	CDD:270855	100/252 (40%)
		S_TKc	105..354	CDD:214567	99/250 (40%)
		ATS1	445..747	CDD:227511
Nek5	XP_008769592.1	PKc_like	3..255	CDD:304357	100/252 (40%)
Nek5	XP_008769592.1	S_TKc	4..255	CDD:214567	100/252 (40%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0589
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D132059at33208
OrthoFinder	1	1.000	-	-		FOG0000168
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.820