DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment niki and rccd1

DIOPT Version :9

Sequence 1:	NP_651293.1	Gene:	niki / 42959	FlyBaseID:	FBgn0045980	Length:	841	Species:	Drosophila melanogaster
Sequence 2:	XP_009296664.1	Gene:	rccd1 / 567613	ZFINID:	ZDB-GENE-030131-3552	Length:	312	Species:	Danio rerio

Alignment Length:	333	Identity:	69/333 - (20%)
Similarity:	111/333 - (33%)	Gaps:	116/333 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly   422 HEILEKRSVLYQLKAFGTCFSMAPIQLPPKAVIVDVAMSDSHFVVVNEDGSAYAWGEGTHGQLG- 485
            ||:..:.:....|.:.|......|...|.|...|.:.:...|.:::..||:.|:||.|:|||||
Zfish    59 HELSAEHTAALPLVSGGFVQHKPPFFHPLKLCAVSLVLGSEHALLLTADGTLYSWGSGSHGQLGH 123

  Fly   486 --LTALEAWKHYPSRMESVRNYHVVSACAGDGFTILVTQAGSLLSCGSNAHLALGQDEQRNYHSP 548
              ||:||                                                        .|
Zfish   124 GALTSLE--------------------------------------------------------DP 132

  Fly   549 KLIARLADVRVEQVAAGLQHVLALSREGAVYVWGTSTCGALGL---GNYQQQQKFPQKILLSHVK 610
            :.:..|..|.::.||||..|..|:|..|.:|:||.:..|.|||   |..:::::
Zfish   133 QAVEALWGVPIKAVAAGNWHSAAVSSGGDLYMWGWNESGQLGLPSRGLEEEKRR----------- 186

  Fly   611 TKPSKIYCGPDTSAVLFANGELHVCGSNDYNKLGFQRSAKITAFKKVQ-LP--------HKVTQA 666
                             .||     ..||...:.....::...|..:| .|        .::::.
Zfish   187 -----------------GNG-----SGNDDQPMNTDEKSQTDVFISIQAFPALVDIANMSEISRI 229

  Fly   667 CFSSTHSVFLVEGGYVYTMGRNAEGQRGIRHCNSVDHPTLVDSVKSRYIVKANCSDQCTIVASED 731
            ...|.|:..:...|.:||.|....||.|....:|.|.||.||...|..:            :.:|
Zfish   230 SCGSRHTAAVTSAGDLYTWGWGQYGQLGHGTEHSTDEPTPVDYFSSHSL------------SVKD 282

  Fly   732 NIITVWGT 739
            .:...|.|
Zfish   283 VVCGSWNT 290

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
niki	NP_651293.1	STKc_Nek	104..359	CDD:270855
		S_TKc	105..354	CDD:214567
		ATS1	445..747	CDD:227511	65/310 (21%)
rccd1	XP_009296664.1	RCC1_2	92..120	CDD:290274	9/27 (33%)
		RCC1	107..156	CDD:278826	23/104 (22%)
		RCC1_2	143..172	CDD:290274	11/28 (39%)
		RCC1	160..239	CDD:278826	18/111 (16%)
		RCC1_2	226..255	CDD:290274	6/28 (21%)
		RCC1	243..292	CDD:278826	17/60 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1062377at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	2.010