DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment niki and sergef

DIOPT Version :9

Sequence 1:	NP_651293.1	Gene:	niki / 42959	FlyBaseID:	FBgn0045980	Length:	841	Species:	Drosophila melanogaster
Sequence 2:	XP_021329502.1	Gene:	sergef / 565673	ZFINID:	ZDB-GENE-061220-11	Length:	397	Species:	Danio rerio

Alignment Length:	378	Identity:	101/378 - (26%)
Similarity:	147/378 - (38%)	Gaps:	86/378 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   447 QLPPKAV--------IVDVAMSDSHFVVVNEDGSAYAWGEGTHGQLGLT-ALEAWKHYPSRMESV 502
            |..|:.|        |..|.....|..::::.|.....|:...|||||. .||........:...
Zfish    32 QAEPRRVESGLQEEQIRAVTGGGGHSALISDSGELLVCGQNHKGQLGLCHTLEIMTFQTCPLPGF 96

  Fly   503 RNYHVVSACAGDGFTILVTQAGSLLSCGSNAHLALGQDEQRNYHSPKLIARLADVRVEQVAAGLQ 567
            .....|| |..| |||::|..|.:|:|||||...||...::.:.:..|:.:.....|..|||||:
Zfish    97 GRVQQVS-CGWD-FTIILTGDGLVLACGSNAFGQLGGSAEKTHSAEPLLLKSFHEPVTSVAAGLR 159

  Fly   568 HVLALSREGAVYVWGTSTCGALGLGNYQQQQKFPQKILLSHVKTK------------PSKIYCGP 620
            |.||.:..|.||.|||      ||.::.::...||.: .||:.:|            ..|:..|.
Zfish   160 HALASTASGCVYQWGT------GLSSHAKRMLNPQPV-PSHLSSKEPCLVPGFAHVTTQKVIAGS 217

  Fly   621 DTSAVLFANGELHVCGSNDYNKLGFQRSAKITAFKKVQLP----------HKVTQACFSSTHSVF 675
            ...|.|..||::.:.|||.:.:|       |:....:.||          .:|:......||.|.
Zfish   218 AHCACLTVNGDVFLWGSNKHGQL-------ISGSLFLPLPVALDRSMLQDERVSDVHSGWTHLVA 275

  Fly   676 LVEGGYVYTMGRNAEGQRGIRHCNSVDHPTLVDSVKSRYI-----VKANCSDQCTIVASEDNIIT 735
            ..|.|.|:|.||:..||.|     ..:|.....|...|.:     |||..........||.|:..
Zfish   276 QTESGRVFTWGRSNYGQLG-----QTNHSMEKQSCDERLVRSPVEVKALFGATQISCGSEHNLAV 335

  Fly   736 V------WG-TRNGLPGIGS--------------------TNCGLG--LQICT 759
            |      || ..:|:.|.||                    ..||.|  :.:|:
Zfish   336 VGGRVFSWGWNEHGMCGDGSLQDITQPQPIPALADAVALLIGCGAGHSMALCS 388

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
niki	NP_651293.1	STKc_Nek	104..359	CDD:270855
		S_TKc	105..354	CDD:214567
		ATS1	445..747	CDD:227511	95/342 (28%)
sergef	XP_021329502.1	RCC1	13..387	CDD:332518	100/375 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1062377at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.010