DRSC/TRiP Functional Genomics Resources

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Protein Alignment niki and RCBTB1

DIOPT Version :9

Sequence 1:NP_651293.1 Gene:niki / 42959 FlyBaseID:FBgn0045980 Length:841 Species:Drosophila melanogaster
Sequence 2:NP_001339429.1 Gene:RCBTB1 / 55213 HGNCID:18243 Length:531 Species:Homo sapiens


Alignment Length:376 Identity:95/376 - (25%)
Similarity:157/376 - (41%) Gaps:29/376 - (7%)


- Green bases have known domain annotations that are detailed below.


  Fly   451 KAVIVDVAMSDSHFVVVNEDGSAYAWGEGTHGQLGLTALEAWKHYPSRMESVRNYHVVSACAGDG 515
            ||.:...:.|::.:|..|::  .:.:|......|| |........|.::|.:....:.|...|.|
Human    23 KACVFGTSASEALYVTDNDE--VFVFGLNYSNCLG-TGDNQSTLVPKKLEGLCGKKIKSLSYGSG 84

  Fly   516 -FTILVTQAGSLLSCGSNAHLALGQDEQRNYHSP-KLIARLADVRVEQVAAGLQHVLALSREGAV 578
             ..:|.|:.|.:.:.|.|.:..||........:| ::...|...:|.:||.|..|.:||:.:|.|
Human    85 PHVLLSTEDGVVYAWGHNGYSQLGNGTTNQGIAPVQVCTNLLIKQVVEVACGSHHSMALAADGEV 149

  Fly   579 YVWGTSTCGALGLGNYQQQQKFPQKIL-LSHVKTKPSKIYCGPDTSAVLFANGELHVCGSNDYNK 642
            :.||.:.||.:|.|: ...|..|:|:. ..|:| :...|.||..:|..:..|||::..|.|...:
Human   150 FAWGYNNCGQVGSGS-TANQPTPRKVTNCLHIK-RVVGIACGQTSSMAVLDNGEVYGWGYNGNGQ 212

  Fly   643 LGFQRSAKITAFKKVQLPHK--VTQACFSSTHSVFLVEGGYVYTMGRNAEGQRGIRHCNSVDHPT 705
            ||...:.......:|...|.  |.|......|::.|.:.|.:|..|.|..||.|..:.|::..|.
Human   213 LGLGNNGNQLTPVRVAALHSVCVNQIVCGYAHTLALTDEGLLYAWGANTYGQLGTGNKNNLLSPA 277

  Fly   706 LVDSVKSRYIVKANCSDQCTIVA-SEDNIITVWGTRNG----LPGIGSTNCGLGLQICTPNMELE 765
            .:...|.|.:..|.|....|..| ::...:.:||...|    ||.:...:|...:..|..     
Human   278 HIMVEKERVVEIAACHSAHTSAAKTQGGHVYMWGQCRGQSVILPHLTHFSCTDDVFACFA----- 337

  Fly   766 LGNNTAAFTNFLASVYKSELILEPVDILALFSSKEQCD-----RGYYVQVH 811
                |.|.:..|.||...:.:.....:...|.|.|..|     .|.|:.||
Human   338 ----TPAVSWRLLSVEHEDFLTVAESLKKEFDSPETADLKFRIDGKYIHVH 384

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
nikiNP_651293.1 STKc_Nek 104..359 CDD:270855
S_TKc 105..354 CDD:214567
ATS1 445..747 CDD:227511 80/305 (26%)
RCBTB1NP_001339429.1 RCC1 1 40..91 11/53 (21%)
ATS1 43..>316 CDD:227511 72/275 (26%)
RCC1 2 93..145 14/51 (27%)
RCC1 3 147..198 17/52 (33%)
RCC1 4 199..250 13/50 (26%)
RCC1 5 252..302 15/49 (31%)
RCC1 6 304..356 12/60 (20%)
BTB_POZ_RCBTB1_CLLD7 350..466 CDD:349662 8/35 (23%)
BACK_RCBTB1 466..531 CDD:350603
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D1062377at2759
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.920

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