DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment niki and nek6

DIOPT Version :9

Sequence 1:	NP_651293.1	Gene:	niki / 42959	FlyBaseID:	FBgn0045980	Length:	841	Species:	Drosophila melanogaster
Sequence 2:	NP_001006700.1	Gene:	nek6 / 448328	XenbaseID:	XB-GENE-956751	Length:	310	Species:	Xenopus tropicalis

Alignment Length:	256	Identity:	98/256 - (38%)
Similarity:	153/256 - (59%)	Gaps:	12/256 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly   102 LANYEKVRVVGQGSFGIAILYRRKS--DGHQIVFKQINLSE-LSPPGRDLAMNEVDVFSKLHHPN 163
            ||:::..:.:|:|.|  :.:||...  |...:..|::.:.| :....|...:.|:|:..:|:|||
Frog    39 LADFKIEKKIGRGQF--SEVYRATCHLDRKPVALKKVQIFEMMDAKARQDCIKEIDLLKQLNHPN 101

  Fly   164 IVSYLGSFIKDNTLLIEMEYADGGTLAQIIA--ERQGKLHFPERYIIAVFEQISSAINYMHSENI 226
            ::.||.|||:||.|.|.:|.||.|.|:|:|.  ::|.:| .|||.:...|.|:.||:.:|||..|
Frog   102 VIKYLDSFIEDNELNIVLELADAGDLSQMIKYFKKQKRL-IPERTVWKYFVQLCSAVEHMHSRRI 165

  Fly   227 LHRDLKTANVFLNRRGIVKIGDFGISKIMNTK-IHAQTVLGTPYYFSPEMCEGKEYDNKSDIWAL 290
            :|||:|.||||:...|:||:||.|:.:..::| ..|.:::|||||.|||......|:.|||||:|
Frog   166 MHRDIKPANVFITATGVVKLGDLGLGRFFSSKTTAAHSLVGTPYYMSPERIHENGYNFKSDIWSL 230

  Fly   291 GCILGEMCCLKKTFAASNLS--ELVTKIMAGNYTPVP-SGYTSGLRSLMSNLLQVEAPRRP 348
            ||:|.||..|:..|....:|  .|..||...:|.|:| ..|:..||.|:|..:..:..:||
Frog   231 GCLLYEMAALQSPFYGDKMSLFSLCQKIEQCDYPPLPKEHYSEKLRELVSMCIYPDPDQRP 291

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
niki	NP_651293.1	STKc_Nek	104..359	CDD:270855	96/254 (38%)
		S_TKc	105..354	CDD:214567	96/253 (38%)
		ATS1	445..747	CDD:227511
nek6	NP_001006700.1	STKc_Nek6	39..306	CDD:270865	98/256 (38%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000168
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R445
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.030