DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment niki and Rcc1

DIOPT Version :9

Sequence 1:	NP_651293.1	Gene:	niki / 42959	FlyBaseID:	FBgn0045980	Length:	841	Species:	Drosophila melanogaster
Sequence 2:	NP_523943.1	Gene:	Rcc1 / 38669	FlyBaseID:	FBgn0002638	Length:	547	Species:	Drosophila melanogaster

Alignment Length:	388	Identity:	82/388 - (21%)
Similarity:	160/388 - (41%)	Gaps:	58/388 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly   390 PAAAYSNVSMELELPTAQTETKQLM------IADTAAPHEILEKRSVLYQLKAFGTCFSMAPIQL 448
            |.|..:.::..||||..:|....::      :.......:|||::             .::|:..
  Fly    21 PKAKRARIAFHLELPKRRTVLGNVLVCGNGDVGQLGLGEDILERK-------------RLSPVAG 72

  Fly   449 PPKAVIVDVAMSDSHFVVVNEDGSAYAWGEGTHGQLGL-TALEAWKHYPSRMESVRNYHVVSACA 512
            .|.|  ||::....|.:|:.:.|..|::|....|.||. |:.:..:..|..::.......:|  |
  Fly    73 IPDA--VDISAGGMHNLVLTKSGDIYSFGCNDEGALGRDTSEDGSESKPDLIDLPGKALCIS--A 133

  Fly   513 GDGFTILVTQAGSLLSCGS--NAHLALGQDEQRNYHSPKLIARLADVRVEQVAAGLQHVLALSRE 575
            ||..:..:.:.|.:.:.||  ::|..:|.....|..:|  |..:.......:|:|..|::.|:..
  Fly   134 GDSHSACLLEDGRVFAWGSFRDSHGNMGLTIDGNKRTP--IDLMEGTVCCSIASGADHLVILTTA 196

  Fly   576 GAVYVWGTSTCGALG-------LGNYQQQQK---FPQKILLSHVKTKPSKI-----YC---GPDT 622
            |.|:..|.:..|.||       .|..::.::   .|.:::::  :.||.:.     ||   ....
  Fly   197 GKVFTVGCAEQGQLGRLSERSISGEGRRGKRDLLRPTQLIIT--RAKPFEAIWATNYCTFMRESQ 259

  Fly   623 SAVLFANGELHVCGSNDYNKLGFQRSAKITAFKKVQLPHK-VTQACFSSTHSVFLVEGGYVYTMG 686
            :.|::|.      |.|::.:|..:...|..|...::...| :........|:|.|........:|
  Fly   260 TQVIWAT------GLNNFKQLAHETKGKEFALTPIKTELKDIRHIAGGQHHTVILTTDLKCSVVG 318

  Fly   687 RNAEGQRGIRHCNS-VDHPTLVDSVKSRYIVKANCSDQCTIVASEDNIITVWGTR-NGLPGIG 747
            |...|:.|:..... |:.||:|..:..: ||...|.:.|:...:.|..:..||:. |...|:|
  Fly   319 RPEYGRLGLGDVKDVVEKPTIVKKLTEK-IVSVGCGEVCSYAVTIDGKLYSWGSGVNNQLGVG 380

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
niki	NP_651293.1	STKc_Nek	104..359	CDD:270855
		S_TKc	105..354	CDD:214567
		ATS1	445..747	CDD:227511	71/325 (22%)
Rcc1	NP_523943.1	RCC1	42..89	CDD:278826	9/61 (15%)
		RCC1	92..141	CDD:278826	12/50 (24%)
		RCC1_2	131..158	CDD:290274	7/28 (25%)
		RCC1	144..193	CDD:278826	11/50 (22%)
		RCC1_2	182..209	CDD:290274	7/26 (27%)
		RCC1	363..414	CDD:278826	6/18 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1062377at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.010