DRSC/TRiP Functional Genomics Resources

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Protein Alignment niki and Herc3

DIOPT Version :9

Sequence 1:NP_651293.1 Gene:niki / 42959 FlyBaseID:FBgn0045980 Length:841 Species:Drosophila melanogaster
Sequence 2:NP_001102101.1 Gene:Herc3 / 362377 RGDID:1307803 Length:1050 Species:Rattus norvegicus


Alignment Length:479 Identity:117/479 - (24%)
Similarity:192/479 - (40%) Gaps:115/479 - (24%)


- Green bases have known domain annotations that are detailed below.


  Fly   454 IVDVAMSDSHFVVVNEDGSAYAWGEGTHGQLGLTALEAWKHYPSRMESVRNYHVVSACAGDGFTI 518
            |:.||..:||.:.:::.|..::||.|:.|||||...|.....|..::.:....::....|:...:
  Rat    86 IIHVACGESHSLALSDRGQLFSWGAGSDGQLGLMTTEDSVAVPRLIQKLNQQTILQVSCGNWHCL 150

  Fly   519 LVTQAGSLLSCGSNAH--LALGQDEQRNYHSPKLIARLADVRVEQVAAGLQHVLALSREGAVYVW 581
            .:...|...:.|.|:|  |.||: |..:..||:.:..|..:.:.|||||..|..|||..|||:.|
  Rat   151 ALAADGQFFTWGKNSHGQLGLGK-EFPSQTSPQRVRSLEGIPLAQVAAGGAHSFALSLSGAVFGW 214

  Fly   582 GTSTCGALGLGNYQQQQKFPQKILLSHVK----TKPSKIYCGPDTSAVLFANGELHVCGSNDYNK 642
            |.:..|.|||.: ::.::.|     .|||    .|...|.||.:.:|||..:|.:...|:....:
  Rat   215 GMNNAGQLGLSD-EKDRESP-----CHVKLLRTQKVVYISCGEEHTAVLTKSGGVFTFGAGSCGQ 273

  Fly   643 LGFQR-SAKITAFKKVQL-PHKVTQACFSSTHSVFLV-EGGYVYTMGRNAEGQRGIRHCNSVDHP 704
            ||... :.::...:.::| ..:|||......|::.|| ..|.:|..|..|:||.|..|..:|..|
  Rat   274 LGHDSVNDEVNPRRVLELMGSEVTQIACGRQHTLALVPSSGLIYAFGCGAKGQLGTGHTCNVKCP 338

  Fly   705 TLV---------------DSVKSRYIVKANCS--DQCTIVAS----------------------- 729
            :.|               |..|.| :||...|  ||..::.|                       
  Rat   339 SPVKGHWAAHSGQLSARADRFKYR-VVKQIFSGGDQTFVLCSTYENSSPAVDFRTVNQAHYTNLI 402

  Fly   730 EDNIITVW----------GTRNGLPGI-GSTNCGLGLQI---------CTPNME-LELGNNTAAF 773
            .|..|.||          .|.||:..| .|..|..|..:         .:|.:. ::|.:....|
  Rat   403 NDETIAVWRQKLTEHNNANTVNGVVQILSSAACWNGSFLEKKIDEHFKTSPKIPGIDLNSTRVLF 467

  Fly   774 TNFLASVYKSELILEPVDILALFSSKEQC----------------------------DRGYYVQV 810
            ...:.|  :..:|||.:     .:|.|.|                            |..||:.:
  Rat   468 EKLMHS--QHSMILEQI-----LNSFESCLIPQLSSSPPDVEAMRIYLILPEFPLLQDSKYYITL 525

  Fly   811 HDVYPLAHSVLVLVDTTTPLISSY 834
              ..|||.::|.|....:.::.::
  Rat   526 --TIPLAMAILRLETNPSKVLDNW 547

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
nikiNP_651293.1 STKc_Nek 104..359 CDD:270855
S_TKc 105..354 CDD:214567
ATS1 445..747 CDD:227511 96/352 (27%)
Herc3NP_001102101.1 ATS1 2..331 CDD:227511 75/251 (30%)
RCC1 313..377 CDD:395335 19/64 (30%)
HECTc 702..1048 CDD:238033
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D1062377at2759
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
32.920

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