DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment niki and Rcbtb1

DIOPT Version :9

Sequence 1:	NP_651293.1	Gene:	niki / 42959	FlyBaseID:	FBgn0045980	Length:	841	Species:	Drosophila melanogaster
Sequence 2:	NP_001101850.1	Gene:	Rcbtb1 / 361050	RGDID:	1308467	Length:	531	Species:	Rattus norvegicus

Alignment Length:	376	Identity:	95/376 - (25%)
Similarity:	156/376 - (41%)	Gaps:	29/376 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly   451 KAVIVDVAMSDSHFVVVNEDGSAYAWGEGTHGQLGLTALEAWKHYPSRMESVRNYHVVSACAGDG 515
            ||.:..::.|::  :.|.:....:.:|......|| |........|.::|::....:.|...|.|
  Rat    23 KACVFGISASEA--IYVTDSDEVFVFGLNYSNCLG-TGDNQSTLVPKKLEALCGKRIKSLSYGSG 84

  Fly   516 -FTILVTQAGSLLSCGSNAHLALGQDEQRNYHSP-KLIARLADVRVEQVAAGLQHVLALSREGAV 578
             ..:|.|:.|.:.:.|.|.:..||........:| ::...|...:|.:||.|..|.:||:.:|.:
  Rat    85 PHVLLSTEDGVVYAWGHNGYSQLGNGTTNQGIAPIQVCTNLLVKQVVEVACGSHHSMALAADGEL 149

  Fly   579 YVWGTSTCGALGLGNYQQQQKFPQKIL-LSHVKTKPSKIYCGPDTSAVLFANGELHVCGSNDYNK 642
            :.||.:.||.:|.|: ...|..|:|:. ..|.| |...|.||..:|..:..:||::..|.|...:
  Rat   150 FAWGYNNCGQVGSGS-TANQPTPRKVTNCLHTK-KVVNIACGQTSSMAVLDSGEVYGWGYNGNGQ 212

  Fly   643 LGFQRSAKITAFKKVQLPHK--VTQACFSSTHSVFLVEGGYVYTMGRNAEGQRGIRHCNSVDHPT 705
            ||...:.......:|...|.  |.|......|::.|.:.|.:|..|.|..||.|....|::..||
  Rat   213 LGLGNNGNQLTPVRVAALHGVCVNQIVCGYAHTLALTDEGLLYAWGANTYGQLGTGSKNNLLSPT 277

  Fly   706 LVDSVKSRYIVKANCSDQCTIVA-SEDNIITVWGTRNG----LPGIGSTNCGLGLQICTPNMELE 765
            .:...|.|.|..|.|....|..| ::...:.:||...|    ||.:...:|...:..|.
  Rat   278 QIMVEKERVIEIAACHSTHTSAAKTQGGHVYMWGQCRGQSVILPHLTHFSCTDDVFACF------ 336

  Fly   766 LGNNTAAFTNFLASVYKSELILEPVDILALFSSKEQCD-----RGYYVQVH 811
               .|.|.:..|.||...:.:.....:...|.|.|..|     .|.|:.||
  Rat   337 ---GTPAVSWRLLSVEHEDFLTVAESLKKEFDSPETADLKFRIDGKYIHVH 384

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
niki	NP_651293.1	STKc_Nek	104..359	CDD:270855
		S_TKc	105..354	CDD:214567
		ATS1	445..747	CDD:227511	80/305 (26%)
Rcbtb1	NP_001101850.1	RCC1	42..89	CDD:395335	9/47 (19%)
		ATS1	<91..363	CDD:227511	73/282 (26%)
		BTB_POZ_RCBTB1_CLLD7	350..466	CDD:349662	8/35 (23%)
		BACK_RCBTB1	466..531	CDD:350603
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1062377at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920