Protein Alignment niki and Nek6

DIOPT Version :10

• Sequence 1: NP_651293.1
• Gene: niki / 42959
• FlyBaseID: FBgn0045980
• Length: 841
• Species: Drosophila melanogaster
• Sequence 2: NP_891998.1
• Gene: Nek6 / 360161
• RGDID: 727779
• Length: 313
• Species: Rattus norvegicus
• Alignment Length: 300
• Identity: 103/300 - (34%)
• Similarity: 159/300 - (53%)
• Gaps: 27/300 - (9%)

  Fly    60 GAASTSLAEAMSSSKAQMPNRQESLLQLSVPRETGVGVAGPELANYEKVRVVGQGSFG----IAI 120
            |.:...|...:..:....|.|..:.|....           .||:::..:.:|:|.|.    ...
  Rat    11 GGSPNHLCHVLGPAHPPDPQRHPNTLSFRC-----------SLADFQIEKKIGRGQFSEVYKATC 64

  Fly   121 LYRRKSDGHQIVFKQINLSE-LSPPGRDLAMNEVDVFSKLHHPNIVSYLGSFIKDNTLLIEMEYA 184
            |..||:    :..|::.:.| :....|...:.|:.:..:|:||||:.||.|||:||.|.|.:|.|
  Rat    65 LLDRKT----VALKKVQIFEMMDAKARQDCVKEIGLLKQLNHPNIIKYLDSFIEDNELNIVLELA 125

  Fly   185 DGGTLAQIIA--ERQGKLHFPERYIIAVFEQISSAINYMHSENILHRDLKTANVFLNRRGIVKIG 247
            |.|.|:|:|.  ::|.:| .|||.:...|.|:.||:.:|||..::|||:|.||||:...||||:|
  Rat   126 DAGDLSQMIKYFKKQKRL-IPERTVWKYFVQLCSAVEHMHSRRVMHRDIKPANVFITATGIVKLG 189

  Fly   248 DFGISKIMNTK-IHAQTVLGTPYYFSPEMCEGKEYDNKSDIWALGCILGEMCCLKKTFAAS--NL 309
            |.|:.:..::: ..|.:::|||||.|||......|:.|||||:|||:|.||..|:..|...  ||
  Rat   190 DLGLGRFFSSETTAAHSLVGTPYYMSPERIHENGYNFKSDIWSLGCLLYEMAALQSPFYGDKMNL 254

  Fly   310 SELVTKIMAGNYTPVP-SGYTSGLRSLMSNLLQVEAPRRP 348
            ..|..||...:|.|:| ..|:..||.|:|..:..:...||
  Rat   255 FSLCQKIEQCDYPPLPGEHYSEKLRELVSMCIYPDPNHRP 294

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
niki	NP_651293.1	STKc_Nek	104..359	CDD:270855	95/255 (37%)
		ATS1	433..749	CDD:444065
Nek6	NP_891998.1	Interaction with ARHGAP33, ANKRA2, CDC42, PRDX3, RAD26L, RBBP6, RPS7 and TRIP4. /evidence=ECO:0000250	1..44		6/43 (14%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..31		3/19 (16%)
		STKc_Nek6_7	44..305	CDD:270863	95/255 (37%)
		Interaction with APBB1. /evidence=ECO:0000250	267..270		1/2 (50%)