DRSC/TRiP Functional Genomics Resources

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Protein Alignment niki and Nek2

DIOPT Version :10

Sequence 1:NP_651293.1 Gene:niki / 42959 FlyBaseID:FBgn0045980 Length:841 Species:Drosophila melanogaster
Sequence 2:NP_572415.1 Gene:Nek2 / 31696 FlyBaseID:FBgn0029970 Length:735 Species:Drosophila melanogaster


Alignment Length:292 Identity:101/292 - (34%)
Similarity:166/292 - (56%) Gaps:10/292 - (3%)


- Green bases have known domain annotations that are detailed below.


  Fly    87 LSVPRETGVGVAGPELANYEKVRVVGQGSFGIAILYRRKSDGHQIVFKQINLSELSPPGRDLAMN 151
            :|.....|:..:...|.:||.:.|:|.||||.....|.||.|....:|.:|..||.....|..::
  Fly     1 MSGEESAGMDFSQKTLQDYEVLAVMGNGSFGTCYKVRDKSTGELFAWKGMNYDELDEAKCDALVS 65

  Fly   152 EVDVFSKLHHPNIVSYLGSFI--KDNTLLIEMEYADGGTLAQIIAE-RQGKLHFPERYIIAVFEQ 213
            |:.|..:|.|||||.|....:  :..::.|.||...||.||||:.. |..:..|.|.||..|..|
  Fly    66 EISVLRQLQHPNIVQYYHHLVNREAKSVYIVMECCAGGDLAQIVQRARSQRQRFEEPYIWRVLFQ 130

  Fly   214 ISSAINYMHSE----NILHRDLKTANVFLNRRGIVKIGDFGISKIM-NTKIHAQTVLGTPYYFSP 273
            :..|:...|::    .|||||:|.||:||:..|..|:||||::::: ..:..|.:.:|||:|.||
  Fly   131 LCRALQVCHNKIPNGTILHRDIKPANIFLDAAGNAKLGDFGLARMLRRDQSFAASFVGTPHYMSP 195

  Fly   274 EMCEGKEYDNKSDIWALGCILGEMCCLKKTFAASNLSELVTKIMAGNYTPVPSGYTSGLRSLMSN 338
            |:.:|::||.|||:||:||::.|||.|:..|......:|..||..|.::.:|:.|::.|:.:::.
  Fly   196 ELVKGRKYDRKSDVWAVGCLVYEMCALRPPFRGRAFDQLSEKIAQGEFSRIPAIYSTDLQEIIAF 260

  Fly   339 LLQVEAPRRPTASEVLVYWIPLIFRSLGKNKG 370
            :|.|:..:||....::.:  ||:.|::.:..|
  Fly   261 MLAVDHEQRPGIEVIIRH--PLVVRNISELDG 290

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
nikiNP_651293.1 STKc_Nek 104..359 CDD:270855 94/262 (36%)
ATS1 433..749 CDD:444065
Nek2NP_572415.1 STKc_Nek2 18..281 CDD:270857 95/264 (36%)
Blue background indicates that the domain is not in the aligned region.

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