DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment niki and png

DIOPT Version :9

Sequence 1:	NP_651293.1	Gene:	niki / 42959	FlyBaseID:	FBgn0045980	Length:	841	Species:	Drosophila melanogaster
Sequence 2:	NP_477492.1	Gene:	png / 31084	FlyBaseID:	FBgn0000826	Length:	291	Species:	Drosophila melanogaster

Alignment Length:	207	Identity:	72/207 - (34%)
Similarity:	108/207 - (52%)	Gaps:	11/207 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly   108 VRVVGQGSFGIAILYR----RKSDGHQIVFKQINLSELSPPGRDLAM--NEVDVFSKLHHPNIVS 166
            |||:|||:||...|..    |.....::..|:|.:..   |..:|.:  .||.:.|:|.||:||.
  Fly    11 VRVLGQGTFGRVFLCHQNEVRGQPERKVCVKRIIVRN---PKTELGLIKEEVYIISQLRHPHIVE 72

  Fly   167 YLGSFIKDNTLLIEMEYADGGTLAQIIAE-RQGKLHFPERYIIAVFEQISSAINYMHSENILHRD 230
            :|.||....|:.|.|||...|||..:|.: ..|.....:..::..|..:...:.|:|...::|||
  Fly    73 FLRSFSHAGTVNIVMEYVPNGTLRDVIQQLPSGTGGVNQERLMGYFRDMVVGLEYLHIRCVIHRD 137

  Fly   231 LKTANVFLNRRGIVKIGDFGISKIMNTKIHAQTVLGTPYYFSPE-MCEGKEYDNKSDIWALGCIL 294
            :|..|:.|:....|||.||||:.:.......|..:|||.|.:|| |....:.|.|||:|:||.:|
  Fly   138 IKPENMLLDANDRVKIADFGIANVHAPSTQLQAGMGTPMYMAPEAMSSQGKVDFKSDVWSLGLVL 202

  Fly   295 GEMCCLKKTFAA 306
            .|:|..:..|||
  Fly   203 YELCLGRSPFAA 214

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
niki	NP_651293.1	STKc_Nek	104..359	CDD:270855	72/207 (35%)
		S_TKc	105..354	CDD:214567	72/207 (35%)
		ATS1	445..747	CDD:227511
png	NP_477492.1	PKc_like	9..>214	CDD:304357	70/205 (34%)
png	NP_477492.1	S_TKc	11..271	CDD:214567	72/207 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45443424
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000168
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.840