Protein Alignment niki and Nek9

DIOPT Version :10

• Sequence 1: NP_651293.1
• Gene: niki / 42959
• FlyBaseID: FBgn0045980
• Length: 841
• Species: Drosophila melanogaster
• Sequence 2: NP_001100217.2
• Gene: Nek9 / 299204
• RGDID: 1307187
• Length: 976
• Species: Rattus norvegicus
• Alignment Length: 719
• Identity: 222/719 - (30%)
• Similarity: 349/719 - (48%)
• Gaps: 119/719 - (16%)

  Fly    96 GVAGPELANYEKVRVVGQGSFGIAILYRRKSDGHQIVFKQINLSELSPPGRDLAMNEVDVFSKLH 160
            |.|..|..:|..:||:|:|:||.|.||||..|...:|:|:::|:.||...|..|:||:.:.:.|.
  Rat    42 GAAEQEELHYIPIRVLGRGAFGEATLYRRTEDDSLVVWKEVDLTRLSEKERRDALNEIVILALLQ 106

  Fly   161 HPNIVSYLGSFIKDNTLLIEMEYADGGTLAQIIAERQGKLHFPERYIIAVFEQISSAINYMHSEN 225
            |.||::|...|:.:.|||||:||.:||.|...|..::.|| |.|..::....||.||::.:|...
  Rat   107 HDNIIAYYNHFMDNTTLLIELEYCNGGNLYDKILRQKDKL-FEEEMVVWYLFQIVSAVSCIHKAG 170

  Fly   226 ILHRDLKTANVFLNRRGIVKIGDFGISKIMNTKIH-AQTVLGTPYYFSPEMCEGKEYDNKSDIWA 289
            |||||:||.|:||.:..::|:||:|::|.:|::.. |:|::|||||.|||:|:|.:|:.||||||
  Rat   171 ILHRDIKTLNIFLTKANLIKLGDYGLAKKLNSEYSMAETLVGTPYYMSPELCQGVKYNFKSDIWA 235

  Fly   290 LGCILGEMCCLKKTFAASNLSELVTKIMAG-NYTPVPSG-YTSGLRSLMSNLLQVEAPRRPTASE 352
            :||::.|:..||:||.|:|...|..||:.| ....|.|. |:.||..|:...|..:..|||||..
  Rat   236 VGCVIFELLTLKRTFDATNPLNLCVKIVQGIRAMEVDSSQYSLGLIQLVHACLDQDPERRPTADA 300

  Fly   353 VLVYWIPLIFRSLGKNKGYSYEDDVGGPGSDQLTAPVPAAAYSNVSMELELPTAQTETKQLMIAD 417
            :|.  :||:     :.:....|:.|     ..|.||......|.|
  Rat   301 LLD--LPLL-----RKRRREMEEKV-----TLLNAPTKRPRSSTV-------------------- 333

  Fly   418 TAAPHEILEKRSVLYQLKAFGTCFSMAPIQLPPKAVIV-------DVAMSDSHFVVVNEDGSAYA 475
            |.||..::..|:....:...|.       ..|.|..::       .|...::||.||..:...|.
  Rat   334 TEAPIAVVTSRTSEVYVWGGGK-------STPQKLDVIKSGCSARQVCAGNTHFAVVTVEKELYT 391

  Fly   476 W-----GEGTHGQLGLTALEAWKHYPSRMESVRNYHVVSACAGDGFTILVTQAGSLLSCGSNAHL 535
            |     |...|||||.....:::. |..:|.::...:.....||.||:.||..|.|.:.||:.:.
  Rat   392 WVNMQGGTKLHGQLGHGDKASYRQ-PKHVEKLQGKAIHQVSCGDDFTVCVTDEGQLYAFGSDYYG 455

  Fly   536 ALGQDE----------QRNY--HSPKLIARLADVRVEQVAAGLQHVLALSREGAVYVWGTSTCGA 588
            .:|.|:          |.|:  .:|          ||||:.|..||:.|:|...||.||....|.
  Rat   456 CMGVDKVSGPEVLEPMQLNFFLSNP----------VEQVSCGDNHVVVLTRNKEVYSWGCGEYGR 510

  Fly   589 LGLGNYQ-----QQQKFPQKILLSHVKTKPSKIYCGPDTSAVLFANGELHVCGSNDYNKLGFQR- 647
            |||.:.:     |:...|:.:::..|:       ||.|.:.:|..:|::..||.|::||||..:
  Rat   511 LGLDSEEDYYTPQRVDVPKALIIVAVQ-------CGCDGTFLLTQSGKVLACGLNEFNKLGLNQC 568

  Fly   648 ---------------SAKITAFKKVQLPHKVTQACFSSTHSVFLVEGGYVYTMGRNAEGQRGIRH 697
                           :...|..|::.. :|:.......||:..:.|.|.:.|.|.|..||.|:.:
  Rat   569 MSGIINHEAYHEVPYTTSFTLAKQLSF-YKIRTIAPGKTHTAAIDERGRLLTFGCNKCGQLGVGN 632

  Fly   698 ------CNSVDHPTLVDSVKSRYIVKANCSDQCTIVASEDNIITVWGT-RNGLPGIGSTNCGLGL 755
                  .|.:..|     :..:.:::.:|.|:.||.|::||.|..||. .||...:..|....|.
  Rat   633 YKKRLGINLLGGP-----LGGKQVIRVSCGDEFTIAATDDNHIFAWGNGGNGRLAMTPTERPHGS 692

  Fly   756 QICT 759
            .|||
  Rat   693 DICT 696

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
niki	NP_651293.1	STKc_Nek	104..359	CDD:270855	109/257 (42%)
		ATS1	433..749	CDD:444065	92/367 (25%)
Nek9	NP_001100217.2	STKc_Nek9	50..297	CDD:270860	105/247 (43%)
		ATS1	371..750	CDD:444065	94/350 (27%)