DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment niki and fin1

DIOPT Version :9

Sequence 1:	NP_651293.1	Gene:	niki / 42959	FlyBaseID:	FBgn0045980	Length:	841	Species:	Drosophila melanogaster
Sequence 2:	NP_593305.1	Gene:	fin1 / 2542237	PomBaseID:	SPAC19E9.02	Length:	722	Species:	Schizosaccharomyces pombe

Alignment Length:	276	Identity:	90/276 - (32%)
Similarity:	144/276 - (52%)	Gaps:	23/276 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly   102 LANYEKVRVVGQGSFGIAILYRRKSDGHQIVFKQINLSELSPPGRDLAMNEVDVFSKLHHPNIVS 166
            :..|:.:..:|.||||.....:|..||..:..|:|:...::...:....:||::...|.|||||.
pombe     1 MEKYKILECIGHGSFGRIYKVQRLKDGALLAQKEIHFGNITRQEKQYIADEVNILRNLKHPNIVQ 65

  Fly   167 YLGSFIKDNTLLIE--MEYADGGTLAQIIAE-RQGKLHFPERYIIAVFEQISSAINYMH------ 222
            |.|..:..:..:|.  |||...|.||.:|.. ::.|..|.|:.::..|.|:..|:...|
pombe    66 YCGEELNRSAQVINLYMEYCGHGDLANLIQRYKEEKKRFTEQEVLKFFTQLLLALYRCHYGENAP 130

  Fly   223 -------------SENILHRDLKTANVFLNRRGIVKIGDFGISKIM-NTKIHAQTVLGTPYYFSP 273
                         .:::||||:|.||:||:....||:||||:||:: ||::..|:.:|||||.||
pombe   131 ACDSQWPREIFHPKQSVLHRDIKPANIFLDENNSVKLGDFGLSKLLDNTRVFTQSYVGTPYYMSP 195

  Fly   274 EMCEGKEYDNKSDIWALGCILGEMCCLKKTFAASNLSELVTKIMAGNYTPVPSGYTSGLRSLMSN 338
            |:.....|..|||:|||||::.|:|.|...|...:..||...|..||.:.....|:..:..|:.:
pombe   196 EIIRSSPYSAKSDVWALGCVIFEICMLTHPFEGRSYLELQRNICQGNLSCWDHHYSDDVFLLIRH 260

  Fly   339 LLQVEAPRRPTASEVL 354
            .|:|.:..|||..::|
pombe   261 CLEVNSDLRPTTYQLL 276

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
niki	NP_651293.1	STKc_Nek	104..359	CDD:270855	90/274 (33%)
		S_TKc	105..354	CDD:214567	89/271 (33%)
		ATS1	445..747	CDD:227511
fin1	NP_593305.1	STKc_Nek2	3..281	CDD:270857	90/274 (33%)
fin1	NP_593305.1	S_TKc	4..281	CDD:214567	90/273 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000168
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R445
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.940